TLR3 antibody (mAb) | Active Motif 40952 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

TLR3 antibody (mAb)

catalog :

40952

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

40C1285

The same clone is also sold as:

Santa Cruz Biotechnology: sc-52961
Invitrogen: MA1-25649
Abcam: ab13915
Abnova: MAB3706

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, FACS

product information

Catalog Number :

40952

Product Name :

TLR3 antibody (mAb)

Host Species :

Mouse

Clonality :

Monoclonal

Size :

100 ug

Clone :

40C1285

Isotype :

IgG1

CrossReactivity :

Human

Background :

TLR3 M-bM-^@M-^S Toll-Like receptor 3 is a member of the Toll-like receptor (TLR) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize specific molecular features associated with pathogens, and mediate the production of cytokines necessary for the development of effective immunity. Many of the TLRs heterodimerize with each other to modulate receptor function. TLR3 expression is increased after exposure to Gram-negative bacteria and to an even greater extent in response to Gram-positive bacteria. TLR3 forms a homodimer and recognizes viral double stranded RNA (dsRNA).

Immunogen :

This antibody was raised against a KLH-conjugated synthetic peptide corresponding to human TLR3.

Uses :

FACS, IHC, IP, WB

Storage :

Antibodies in solution can be stored at -80M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.