D4-GDI antibody (mAb) | Active Motif 40941 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

D4-GDI antibody (mAb)

catalog :

40941

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

97A1015

reactivity :

human

application :

western blot, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 1	Fujiwara M, Okamoto M, Hori M, Suga H, Jikihara H, Sugihara Y, et al. Radiation-Induced RhoGDI? Cleavage Leads to Perturbation of Cell Polarity: A Possible Link to Cancer Spreading. J Cell Physiol. 2016;231:2493-505 pubmed publisher

product information

Catalog Number :

40941

Product Name :

D4-GDI antibody (mAb)

Host Species :

Mouse

Clonality :

Monoclonal

Size :

100 ug

Clone :

97A1015

Isotype :

IgG1

CrossReactivity :

Human

Background :

D4-GDI (Rho GDP dissociation inhibitor beta or ARHGDIB) plays an important role in the activation of the superoxide (O2-)-generating NADPH oxidase of phagocytes. The mechanisms involving cleavage of D4-GDI (Rho GDP) with apoptosis are not presently known. However, activation of the Jun N-terminal kinase, a regulator of apoptosis, may be one of the mechanisms.

Immunogen :

This antibody was raised against a synthetic peptide corresponding to amino acid residues in the Fas-induced cleavage site of human D4-GDI.

Uses :

IP, WB

Storage :

Antibodies in solution can be stored at -80M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.