This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Active Motif
other brands :
Geneka Biotechnology
product type :
antibody
product name :
Osteoprotegerin (OPG) antibody (mAb)
catalog :
40938
quantity :
100 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
98A1071

The same clone is also sold as:
reactivity :
human
application :
western blot
product information
Catalog Number :
40938
Product Name :
Osteoprotegerin (OPG) antibody (mAb)
Host Species :
Mouse
Clonality :
Monoclonal
Size :
100 ug
Clone :
98A1071
Isotype :
IgG1
CrossReactivity :
Human
Background :
Osteoprotegerin (OPG) / osteoclastogenesis inhibitory factor (OCIF) is a cytokine that can inhibit the production of osteoclasts. It is a member of the tumor necrosis factor (TNF) receptor superfamily. It is a basic glycoprotein comprising 401 amino acid residues arranged into 7 structural domains. It is found as either a 60 kDa monomer or 120 kDa dimer linked by disulfide bonds. Osteoprotegerin inhibits the differentiation of osteoclast precursors into osteoclasts and also regulates the resorption of osteoclasts in vitro and in vivo. Osteoprotegerin is a RANK homolog, and works by binding to RANKL ligand on osteoblast/stromal cells, thus blocking the RANKL-RANK ligand interaction between osteoblast/stromal cells and osteoclast precursors. This has the effect of inhibiting the differentiation of the osteoclast precursor into a mature osteoclast.
Immunogen :
This Osteoprotegerin (OPG) antibody was raised against a peptide corresponding to amino acid residues 20-37 of human Osteoprotegerin (OPG).
Uses :
WB
Storage :
Antibodies in solution can be stored at -80M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
company information
Active Motif
1914 Palomar Oaks Way, Suite 150
Carlsbad, CA 92008
sales@activemotif.com
http://www.activemotif.com
1-760-431-1263
headquarters: USA