Caspase-8 antibody (mAb) | Active Motif 40930 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

Caspase-8 antibody (mAb)

catalog :

40930

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

90A992

The same clone is also sold as:

Rockland Immunochemicals: 200-301-H64
Invitrogen: MA1-41280
Novus Biologicals: NBP2-80616, NB100-56527
OriGene: TA336388

reactivity :

human

application :

western blot, immunohistochemistry, FACS

product information

Catalog Number :

40930

Product Name :

Caspase-8 antibody (mAb)

Host Species :

Mouse

Clonality :

Monoclonal

Size :

100 ug

Clone :

90A992

Isotype :

IgG1

CrossReactivity :

Human

Background :

Caspase-8 (CASP8 or apoptosis-related cysteine peptidase 8) is the most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adaptor molecule FADD recruits it to either receptor. Caspase-8 cleaves and activates Caspase-3, Caspase-4, Caspase-6, Caspase-7, Caspase-9 and Caspase-10.

Immunogen :

This antibody was raised against a synthetic peptide corresponding to amino acid residues 217-222 of human Caspase-8.

Uses :

FACS, IHC, WB

Storage :

Antibodies in solution can be stored at -80M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.