PLZF antibody (mAb) | Active Motif 39987 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

PLZF antibody (mAb)

catalog :

39987

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2A9

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; human; fig 2 western blot; human; fig 2	Felli N, Errico M, Pedini F, Petrini M, Puglisi R, Bellenghi M, et al. AP2Î± controls the dynamic balance between miR-126&126* and miR-221&222 during melanoma progression. Oncogene. 2016;35:3016-26 pubmed publisher

product information

Catalog Number :

39987

Product Name :

PLZF antibody (mAb)

Host Species :

Mouse

Clonality :

Monoclonal

Size :

100 ug

Clone :

2A9

Isotype :

IgG2a

CrossReactivity :

Human

Background :

PLZF (Promyelocytic Leukemia Zinc-Finger protein) is a member of the POK (POZ and KrM-CM-<ppel) family of transcriptional repressors. PLZF is expressed in early, but not differentiated, hematopoietic cells, and is required for spermatogonial stem cell maintenance. In addition, PLZF regulates genes involved in cellular proliferation and differentiation (cyclin A2, Myc and Hox genes) and targeted deletion of PLZF in mice results in limb and axial skeleton and limb deformations.

Immunogen :

This PLZF antibody was raised against a recombinant protein corresponding to full-length mouse PLZF with a GST epitope tag.

Uses :

ChIP, IF, IP, WB

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Product References :

References: This antibody has been used in the following references: ChIP: Doulatov S et al. (2009) Genes Dev 23: 2076-2087.IF: Koken MH et al. (1997) PNAS 94: 10255-10260.WB: Doulatov S et al. (2009) Genes Dev 23: 2076-2087. Shaknovich R et al. (1998) Molec Cell Biol 18: 5533-5545.