HP1M-NM-3 antibody (mAb) | Active Motif 39981 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

HP1M-NM-3 antibody (mAb)

catalog :

39981

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2MOD-1G6

The same clone is also sold as:

Invitrogen: MA3-054

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; fig 10	Sobecki M, Mrouj K, Camasses A, Parisis N, Nicolas E, LlÃ¨res D, et al. The cell proliferation antigen Ki-67 organises heterochromatin. elife. 2016;5:e13722 pubmed publisher
immunohistochemistry - paraffin section; human; loading ...; fig 3d	Mishima Y, Jayasinghe C, Lu K, Otani J, Shirakawa M, Kawakami T, et al. Nucleosome compaction facilitates HP1Î³ binding to methylated H3K9. Nucleic Acids Res. 2015;43:10200-12 pubmed publisher
chromatin immunoprecipitation; human immunocytochemistry; human; 1:200 western blot; human; 1:1000	Boros J, Arnoult N, Stroobant V, Collet J, Decottignies A. Polycomb repressive complex 2 and H3K27me3 cooperate with H3K9 methylation to maintain heterochromatin protein 1? at chromatin. Mol Cell Biol. 2014;34:3662-74 pubmed publisher
	Zaidan N, Sridharan R. HP1γ regulates H3K36 methylation and pluripotency in embryonic stem cells. Nucleic Acids Res. 2020;48:12660-12674 pubmed publisher
	Wike C, Graves H, Hawkins R, Gibson M, Ferdinand M, Zhang T, et al. Aurora-A mediated histone H3 phosphorylation of threonine 118 controls condensin I and cohesin occupancy in mitosis. elife. 2016;5:e11402 pubmed publisher

product information

Catalog Number :

39981

Product Name :

HP1M-NM-3 antibody (mAb)

Host Species :

Mouse

Clonality :

Monoclonal

Size :

100 ug

Clone :

2MOD-1G6

Isotype :

IgG1k

CrossReactivity :

Human, Mouse

Background :

Heterochromatin Protein 1 gamma (HP1 gamma) is one of the mammalian homologues of Drosophila HP1, first identified through its role in the maintenance of regions of the genome in a heterochromatic state. HP1 gamma contains a chromo domain and a chromo shadow domain. Through the chromo domain, HP1 proteins are recruited to regions of chromatin that exhibit methylation of lysine 9 of histone H3.

Immunogen :

This HP1M-NM-3 antibody was raised against recombinant full-length mouse HP1M-NM-3.

Uses :

ELISA, ICC, IF, IHC, IP, WB

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Product References :

References: IF: Nielsen AL et al. (1999) EMBO J 22: 6385-6395. WB: Nielsen AL et al. (1999) EMBO J 22: 6385-6395.