Lamin A, mature antibody (mAb) | Active Motif 39961 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

Lamin A, mature antibody (mAb)

catalog :

39961

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4A4

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

product information

Catalog Number :

39961

Product Name :

Lamin A, mature antibody (mAb)

Host Species :

Mouse

Clonality :

Monoclonal

Size :

100 ug

Clone :

4A4

Isotype :

IgG1

CrossReactivity :

Human

Background :

Nuclear lamins are intermediate filament proteins that are the major structural component of the nuclear lamina on the inner surface of the nuclear envelope. Lamins A and Lamins C are splice variants of the Lamin A gene. Lamin A/C (CDCD1, LMN1, EMD2) expression is a hallmark of embryonic stem cell differentiation. In addition to adding structural integrity to the nucleus, lamins contribute to the makeup of the nuclear matrix. Lamins also help organize interphase chromatin through interactions with several chromatin proteins, including histones and Lap2, such that alteration in lamin organization results in disruption of DNA replication, transcription and RNA processing.

Immunogen :

This Lamin A, mature antibody was raised against a peptide within the C-terminus of mature human Lamin A.

Uses :

IF, IP, WB

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Product References :

References: This antibody has been used in the following references:WB: Roblek M et al. (2010) PLoS One 5: e10604.