Sox2 antibody (pAb) | Active Motif 39823 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

Sox2 antibody (pAb)

catalog :

39823

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - frozen section

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:50; loading ...; fig 4 s1c	Mapps A, Boehm E, Beier C, Keenan W, Langel J, Liu M, et al. Satellite glia modulate sympathetic neuron survival, activity, and autonomic function. elife. 2022;11: pubmed publisher
immunohistochemistry - frozen section; mouse; 1:2000	Jones K, Han J, Debruyne J, Philpot B. Persistent neuronal Ube3a expression in the suprachiasmatic nucleus of Angelman syndrome model mice. Sci Rep. 2016;6:28238 pubmed publisher

product information

Catalog Number :

39823

Product Name :

Sox2 antibody (pAb)

Host Species :

Rabbit

Clonality :

Polyclonal

Size :

100 ul

Isotype :

Serum

CrossReactivity :

Human

Background :

Sox2 (SRY related HMG BOX gene 2) is a DNA binding transcription factor and a member of the SOX family of proteins. SOX proteins have an HMG box that binds DNA. Sox2 forms a complex with Oct4 and controls the expression of a number of genes involved in embryonic. Sox2 is critical for early embryogenesis and for embryonic stem cell pluripotency and thus can serve as a stem cell marker. Overexpression of Sox2 (along with Oct4, KLF4 and c-Myc) can transform mouse fibroblasts into a state resembling embryonic stem cells (ES cells), referred to as Induced Pluripotency. Defects in Sox2 are the cause of microphthalmia syndromic type 3.

Immunogen :

This Sox2 antibody was raised against a peptide corresponding to amino acids amino acids 111-140 mouse Sox2.

Uses :

ChIP, IF, IHC, IP, WB

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Product References :

References: This antibody was used as described inTompkins, D.H. et al. (2009) PLoS One 4: e8248.