Sp1 non-phospho antibody (pAb) | Active Motif 39809 product information

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product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

Sp1 non-phospho antibody (pAb)

catalog :

39809

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

Catalog Number :

39809

Product Name :

Sp1 non-phospho antibody (pAb)

Host Species :

Rabbit

Clonality :

Polyclonal

Size :

100 ul

Isotype :

IgG

CrossReactivity :

Human

Background :

Sp1 (specificity protein 1) is a human transcription factor involved in gene expression in the early development of an organism. The protein is 785 amino acids long, with a molecular weight of 81 kDa. The SP1 transcription factor contains a zinc finger protein motif, by which it binds directly to DNA and enhances gene transcription. Its zinc fingers are of the Cys2/His2 type and bind the consensus sequence 5M-bM-^@M-2-(G/T)GGGCGG(G/A)(G/A)(C/T)-3M-bM-^@M-2 (GC box element). It was discovered in 1983 and has since been modified to form Sp1C, which has a zinc finger protein DNA binding domain.Sp1 contains two SQ/TQ domains, which are found in proteins phosphorylated by the DNA-damage response transducer/effector kinase ATM.

Immunogen :

Peptide containing serine 101 of human SP1.

Uses :

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.