MEIS 1/2/3 antibody (mAb) | Active Motif 39795 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

MEIS 1/2/3 antibody (mAb)

catalog :

39795

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9.2.7

The same clone is also sold as:

Santa Cruz Biotechnology: sc-101850

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, EMSA, chromatin immunoprecipitation, immunohistochemistry - paraffin section

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:100; loading ...; fig 3h	Munro D, Wineberg Y, Tarnick J, Vink C, Li Z, Pridans C, et al. Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development. elife. 2019;8: pubmed publisher
immunocytochemistry; human; 1:300	Takasato M, Er P, Chiu H, Maier B, Baillie G, Ferguson C, et al. Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature. 2015;526:564-8 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:100	Hilliard S, Yao X, El Dahr S. Mdm2 is required for maintenance of the nephrogenic niche. Dev Biol. 2014;387:1-14 pubmed publisher

product information

Catalog Number :

39795

Product Name :

MEIS 1/2/3 antibody (mAb)

Host Species :

Mouse

Clonality :

Monoclonal

Size :

100 ug

Clone :

9.2.7

Isotype :

IgG1

CrossReactivity :

Human, Mouse

Background :

The MEIS family or proteins (Myeloid Ecotropic viral Integration Site homologues) encode proteins that function as cofactors for the Homeobox (HOX) proteins. Homeobox genes play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. MEIS and a functionally related protein Pbx belong to the TALE (Three Amino acid Loop Extension) homeodomain superfamily of proteins. The role of MEIS proteins in the regulation of transcription is as yet unclear.

Immunogen :

This MEIS antibody was raised against a recombinant protein corresponding to amino acids amino acids 50-390 mouse MEIS1.

Uses :

ChIP, EMSA, IHC, IP, WB

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Product References :

References: This antibody was used in applications as described below ChIP: Deramaudt, T.B. et al. (2006) J Biol Chem 281: 38385-38395; Shim, S. et al. (2007) Mol Cell Biol 27: 1614-1630. EMSA: Shim, S. et al. (2007) Mol Cell Biol 27: 1614-1630; Rave-Harel, N. et al. (2004) J Biol Chem 279: 30287-30297. IHC: Shim, S. et al. (2007) Mol Cell Biol 27: 1614-1630. WB: Fiskus, W. (2006) Mol Cancer Ther 5: 3096-3104; Rave-Harel, N. et al. (2004) J Biol Chem 279: 30287-30297; Shim, S. et al. (2007) Mol Cell Biol 27: 1614-1630