TORC2 antibody (pAb) | Active Motif 39779 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

TORC2 antibody (pAb)

catalog :

39779

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot

product information

Catalog Number :

39779

Product Name :

TORC2 antibody (pAb)

Host Species :

Rabbit

Clonality :

Polyclonal

Size :

100 ul

Isotype :

Serum

CrossReactivity :

Human, Mouse

Background :

TORC2 (Transducer of regulated cAMP response element-binding protein 2) / CRTC2 (CREB-regulated transcription coactivator 2) is a coactivator of transcription through the CREB1 signaling pathway, independent of phosphorylation at serine 133. Involved in metabolic signaling pathways, it is responsive to glucagon signaling and regulates gluconeogenesis. It is a potent activator of mitochondrial biogenesis in muscle cells. TORC2 / CRTC2 is inactivated by phosphorylation at serine 171 (in response to both insulin signaling and the activation of AMPK), which facilitates recognition by 14-3-3 protein and subsequent translocation to the cytoplasm.

Immunogen :

This TORC2 / CRTC2 antibody was raised against a peptide at the C-terminus of human TORC2.

Uses :

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.