Estrogen Receptor M-NM-2 antibody (mAb) | Active Motif 39767 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

Estrogen Receptor M-NM-2 antibody (mAb)

catalog :

39767

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CO1531

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 1

Reference
Luo M, Ling T, Xie W, Sun H, Zhou Y, Zhu Q, et al. NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells. Stem Cells. 2013;31:1278-86 pubmed publisher

product information

Catalog Number :

39767

Product Name :

Estrogen Receptor M-NM-2 antibody (mAb)

Host Species :

Mouse

Clonality :

Monoclonal

Size :

100 ug

Clone :

CO1531

Isotype :

IgG2a

CrossReactivity :

Human

Background :

ERM-NM-2 (estrogen receptor M-NM-2) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding and activation of transcription. ERM-NM-2 localizes to the nucleus where it may form a homodimer or a heterodimer with ER alpha. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer and osteoporosis.

Immunogen :

This Estrogen Receptor beta antibody was raised against a recombinant protein corresponding to amino acids 212-477 of human Estrogen Receptor beta.

Uses :

ICC, IF, IP, WB

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Product References :

References: This antibody was used in the various applications as described: Immunoprecipitation: Leong, H. et al. (2005) Molec Endo 19: 2930-2942. Immunocytochemistry: Dan, P. et al. (2002) Am J Physiol Heart Circ Physiol 284: H1295-H1306. Western blotting: Dan, P. et al. (2002) Am J Physiol Heart Circ Physiol 284: H1295-H1306and Penza, M. et al. (2006) Endocrinology 147: 5740-5751