PARP-2 antibody (pAb) | Active Motif 39743 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

PARP-2 antibody (pAb)

catalog :

39743

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunoprecipitation, chromatin immunoprecipitation

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig s1f	Sellou H, Lebeaupin T, Chapuis C, Smith R, Hegele A, Singh H, et al. The poly(ADP-ribose)-dependent chromatin remodeler Alc1 induces local chromatin relaxation upon DNA damage. Mol Biol Cell. 2016;27:3791-3799 pubmed
western blot; human; 1:1000	Grundy G, Polo L, Zeng Z, Rulten S, Hoch N, Paomephan P, et al. PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2). Nat Commun. 2016;7:12404 pubmed publisher

product information

Catalog Number :

39743

Product Name :

PARP-2 antibody (pAb)

Host Species :

Rabbit

Clonality :

Polyclonal

Size :

100 ul

Isotype :

IgG

CrossReactivity :

Human

Background :

PARP-2 encodes a chromatin-associated enzyme, a poly-ADP ribosyl transferase, which modifies various nuclear proteins by poly-ADP ribosylation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation and tumor transformation. It also plays a role in the regulation of the molecular events involved in the recovery of cells from DNA damage. PARP-2 is cleaved by caspase enzymes during the process of apoptosis.

Immunogen :

This PARP-2 antibody was raised against a recombinant protein corresponding to the C-terminal region of human PARP-2.

Uses :

ChIP, IP, WB

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.