Bub1 antibody (mAb) | Active Motif 39735 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

Bub1 antibody (mAb)

catalog :

39735

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

14H5

The same clone is also sold as:

Rockland Immunochemicals: 200-301-900
ImmuQuest: IQ198, IQ255
Invitrogen: MA1-5755, MA5-46547
Santa Cruz Biotechnology: sc-47743

reactivity :

human, mouse

application :

western blot, immunocytochemistry

product information

Catalog Number :

39735

Product Name :

Bub1 antibody (mAb)

Host Species :

Mouse

Clonality :

Monoclonal

Size :

100 ug

Clone :

14H5

Isotype :

IgG

CrossReactivity :

Human, Mouse

Background :

Bub1 is a serine-threonine protein kinase and an important regulator of cell division. It is essential for the G2/M mitotic spindle assembly/integrity checkpoint as well as critical for chromosome alignment. Bub1 is required for the assembly of a large number of proteins at the kinetochore, including CENP-E, CENP-F, BUB1B, MAD2L1 and PLK1. It plays a role in sister chromatid cohesion and it serves as a substrate for the anaphase-promoting complex. Bub1 mediates cell death in response to chromosome mis-segregation and acts to suppress spontaneous tumorigenesis.

Immunogen :

This Bub1 antibody was raised against a recombinant protein corresponding to amino acids 281-419 of human Bub1.

Uses :

IF, WB

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Product References :

References: Liu, ST et al, 2003. Nat Cell Biol 5: 341-345.Liu, ST et al, 2006. J Cell Biol 175: 41-53.