L3MBTL2 antibody (pAb) | Active Motif 39569 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

L3MBTL2 antibody (pAb)

catalog :

39569

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunoprecipitation, chromatin immunoprecipitation

citations: 2

Published Application/Species/Sample/Dilution	Reference
chromatin immunoprecipitation; mouse; fig 5??s1.c western blot; mouse; 1:1000; fig 3b western blot; human; 1:1000; loading ...; fig 3f	Mathsyaraja H, Catchpole J, Freie B, Eastwood E, Babaeva E, Geuenich M, et al. Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness. elife. 2021;10: pubmed publisher
western blot; mouse; loading ...; fig 1c	Endoh M, Endo T, Shinga J, Hayashi K, Farcas A, Ma K, et al. PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes. elife. 2017;6: pubmed publisher

product information

Catalog Number :

39569

Product Name :

L3MBTL2 antibody (pAb)

Host Species :

Rabbit

Clonality :

Polyclonal

Size :

200 ul

Isotype :

Serum

CrossReactivity :

Human

Background :

L3MBTL2 (Lethal (3) malignant brain tumor-like 2 protein) is a putative member of the polycomb group family and is the human homolog of Drosophila Sfmbt, critical for Hox gene silencing. L3MBTL2 contains one FCS-type zinc finger and four MBT (malignant brain tumor) repeats. L3MBTL2 associates with chromatin-remodeling complexes and helps inhibit the expression of proteins that trigger the cells into mitosis. L3MBTL2 is a part of a complex involved in the G0 phase of the cell cycle. This complex contains other proteins such as E2F-6, Max or HP1 gamma, and participates in transcriptional repression.

Immunogen :

This L3MBTL2 antibody was raised against a His-tagged fusion protein containing amino acids 1-230 of human L3MBTL2.

Uses :

ChIP, IP, WB

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.