HIRA antibody (mAb) | Active Motif 39557 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

HIRA antibody (mAb)

catalog :

39557

quantity :

200 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

WC119.2H11

The same clone is also sold as:

Abnova: MAB8967

reactivity :

human, mouse

application :

western blot, immunoprecipitation

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 4c	Huang T, Fowler F, Chen C, Shen Z, SLECKMAN B, Tyler J. The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells. Mol Cell. 2018;69:879-892.e5 pubmed publisher
western blot; mouse; loading ...; fig 1a immunoprecipitation; human; loading ...; fig 2d western blot; human; loading ...; fig 1b	Yang J, Song T, Jo C, Park J, Lee H, Song I, et al. Differential regulation of the histone chaperone HIRA during muscle cell differentiation by a phosphorylation switch. Exp Mol Med. 2016;48:e252 pubmed publisher
	Li Y, Jiao J. Histone chaperone HIRA regulates neural progenitor cell proliferation and neurogenesis via Î²-catenin. J Cell Biol. 2017;216:1975-1992 pubmed publisher

product information

Catalog Number :

39557

Product Name :

HIRA antibody (mAb)

Host Species :

Mouse

Clonality :

Monoclonal

Size :

200 ug

Clone :

WC119.2H11

Isotype :

IgG

CrossReactivity :

Human, Mouse

Background :

HIRA (DGCR1, TUP1) is a histone chaperone that preferentially places the variant Histone H3.3 in nucleosomes, replacing canonical Histone H3 during the cell cycle. HIRA is required for the periodic repression of histone gene transcription during the cell cycle and when complexed with ASF1M-NM-1 is involved in the formation of the senescence-associated heterochromatin foci.

Immunogen :

This HIRA antibody was raised against a GST-fusion protein containing residues 421-729 of human HIRA.

Uses :

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.