MALT1 antibody (mAb) | Active Motif 39395 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

MALT1 antibody (mAb)

catalog :

39395

quantity :

200 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

Catalog Number :

39395

Product Name :

MALT1 antibody (mAb)

Host Species :

Mouse

Clonality :

Monoclonal

Size :

200 ug

Isotype :

IgG

CrossReactivity :

Human

Background :

MALT1 enhances Bcl10-induced activation of NFM-NM-:B and is also involved in nuclear export of Bcl10. MALT1 binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. MALT1 dependent Bcl10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion. MALT1 was independently identified as a protein of 824 amino acids, and human MALT2 isoform b is an amino acid protein of 813 amino acids. MALT1 is thought to play a role in NFM-NM-:B signaling by enhancing NFM-NM-:B (NFM-NM-:B p50 and NFM-NM-:B p65) activation through interaction with Bcl10. Interaction between MALT1 and Bcl10 mediates IKK (IKKM-NM-1, IKKM-NM-2 Clone 10AG2, IKKM-NM-2 Clone 10A9B6, IKKi/IKKM-NM-5 and IKKM-NM-3) activation in vitro through facilitating the ubiquitination of NEMO by the ubiquitin conjugating enzyme UBC13.

Immunogen :

This MALT1 antibody was raised against a recombinant protein corresponding to amino acids 701-808 of mouse MALT1.

Uses :

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.