Ikaros antibody (mAb) | Active Motif 39355 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

Ikaros antibody (mAb)

catalog :

39355

quantity :

200 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2A9

reactivity :

human, mouse

application :

western blot

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human	Yeung F, Chung E, Guess M, Bell M, Leinwand L. Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos. Nucleic Acids Res. 2012;40:7303-18 pubmed publisher

product information

Catalog Number :

39355

Product Name :

Ikaros antibody (mAb)

Host Species :

Mouse

Clonality :

Monoclonal

Size :

200 ug

Clone :

2A9

Isotype :

IgG

CrossReactivity :

Mouse

Background :

Ikaros is a transcription factor that plays a critical role in the control of lymphohematopoiesis and immune regulation. All Ikaros isoforms share a common C-terminal domain that contains a transcription activation motif and two zinc finger motifs required for hetero- and homo-dimerization among the Ikaros isoforms, and for interactions with other proteins. Ikaros is abundantly expressed in pituitary mammosomatotrophs, where it deacetylates Histone H3 sites on the proximal growth hormone (GH) promoter to silence gene expression.

Immunogen :

This Ikaros antibody was raised against a recombinant protein corresponding to the N-terminal half of mouse Ikaros.

Uses :

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.