JARID1C antibody (pAb) | Active Motif 39229 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

JARID1C antibody (pAb)

catalog :

39229

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunoprecipitation, chromatin immunoprecipitation

product information

Catalog Number :

39229

Product Name :

JARID1C antibody (pAb)

Host Species :

Rabbit

Clonality :

Polyclonal

Size :

200 ul

Isotype :

Serum

CrossReactivity :

Human, Mouse

Background :

JARID1C is a member of a family of histone demethylase enzymes that contain a Jumonji-N (Jmj-N) and Jumonji-C (Jmj-C) domain in addition to an AT-rich interacting domain (ARID). JARID1C also contains 2 PHD domains and a PLU-1 domain, and a putative DNA binding module. JARID1C demethylates histone H3 that has been di- or trimethylated at lysine 4, and functions as a repressor of transcription. JARID1C also participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Mutations in the JARID1C gene have been associated with X-linked mental retardation.

Immunogen :

This JARID1C antibody was raised against a peptide corresponding the C-terminus of human JARID1C.

Uses :

ChIP, IP, WB

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.