Histone H2A antibody (pAb) | Active Motif 39209 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

Histone H2A antibody (pAb)

catalog :

39209

quantity :

100 ug

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

citations: 1

Reference
Bao J, Rousseaux S, Shen J, Lin K, Lu Y, Bedford M. The arginine methyltransferase CARM1 represses p300•ACT•CREMτ activity and is required for spermiogenesis. Nucleic Acids Res. 2018;46:4327-4343 pubmed publisher

product information

Catalog Number :

39209

Product Name :

Histone H2A antibody (pAb)

Host Species :

Rabbit

Clonality :

Polyclonal

Size :

100 ug

Isotype :

IgG

CrossReactivity :

Human

Background :

Histone H2A is one of the core components of the nucleosome. The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points. Histone H1 is responsible for establishing higher-order chromatin structure.Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation; these modifications play a major role in regulating gene expression.

Immunogen :

This Histone H2A antibody was raised against a mixture of synthetic peptides corresponding to amino acid residues 1-5 and 81-96 of human Histone H2A.

Uses :

Storage :

Antibodies in solution can be stored at -80M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.