| Published Application/Species/Sample/Dilution | Reference |
|---|
- ChIP-Seq; human; loading ...; fig 5a
| Wan C, Mahara S, Sun C, Doan A, Chua H, Xu D, et al. Genome-scale CRISPR-Cas9 screen of Wnt/β-catenin signaling identifies therapeutic targets for colorectal cancer. Sci Adv. 2021;7: pubmed publisher |
- ChIP-Seq; mouse; loading ...; fig 4p
| Pivetti S, Fernandez Perez D, D Ambrosio A, Barbieri C, Manganaro D, Rossi A, et al. Loss of PRC1 activity in different stem cell compartments activates a common transcriptional program with cell type-dependent outcomes. Sci Adv. 2019;5:eaav1594 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 5a
| Chen X, Zhi X, Wang J, Su J. RANKL signaling in bone marrow mesenchymal stem cells negatively regulates osteoblastic bone formation. Bone Res. 2018;6:34 pubmed publisher |
- ChIP-Seq; human; loading ...; fig 5b
| Stewart E, McEvoy J, Wang H, Chen X, Honnell V, Ocarz M, et al. Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses. Cancer Cell. 2018;34:411-426.e19 pubmed publisher |
- ChIP-Seq; zebrafish ; fig s1a
| Murphy P, Wu S, James C, Wike C, Cairns B. Placeholder Nucleosomes Underlie Germline-to-Embryo DNA Methylation Reprogramming. Cell. 2018;172:993-1006.e13 pubmed publisher |
- ChIP-Seq; mouse; loading ...; fig 4a
| Fujita J, Freire P, Coarfa C, Benham A, Gunaratne P, Schneider M, et al. Ronin Governs Early Heart Development by Controlling Core Gene Expression Programs. Cell Rep. 2017;21:1562-1573 pubmed publisher |
- ChIP-Seq; mouse; loading ...; fig 1b
| Cruz Molina S, Respuela P, Tebartz C, Kolovos P, Nikolic M, Fueyo R, et al. PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation. Cell Stem Cell. 2017;20:689-705.e9 pubmed publisher |
- chromatin immunoprecipitation; brewer's yeast; loading ...; fig s2a
- western blot; brewer's yeast; loading ...; fig 1a
| Young C, Hillyer C, Hokamp K, Fitzpatrick D, Konstantinov N, Welty J, et al. Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast. BMC Genomics. 2017;18:107 pubmed publisher |
- chromatin immunoprecipitation; human; fig s2
| Ho T, Huang J, Zhou N, Zhang Z, Koirala P, Zhou X, et al. Regulation of PCGEM1 by p54/nrb in prostate cancer. Sci Rep. 2016;6:34529 pubmed publisher |
- chromatin immunoprecipitation; human; fig 5
| Amabile A, Migliara A, Capasso P, Biffi M, Cittaro D, Naldini L, et al. Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing. Cell. 2016;167:219-232.e14 pubmed publisher |
- ChIP-Seq; Xenopus laevis; fig 6b
| Walentek P, Quigley I, Sun D, Sajjan U, Kintner C, Harland R. Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis. elife. 2016;5: pubmed publisher |
- ChIP-Seq; mouse; loading ...; fig 4
| Omata Y, Nakamura S, Koyama T, Yasui T, Hirose J, Izawa N, et al. Identification of Nedd9 as a TGF-?-Smad2/3 Target Gene Involved in RANKL-Induced Osteoclastogenesis by Comprehensive Analysis. PLoS ONE. 2016;11:e0157992 pubmed publisher |
- western blot; mouse; fig s6d
| Lu C, Jain S, Hoelper D, Bechet D, Molden R, Ran L, et al. Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape. Science. 2016;352:844-9 pubmed publisher |
- chromatin immunoprecipitation; human; fig 6
| Kushwaha R, Jagadish N, Kustagi M, Mendiratta G, Seandel M, Soni R, et al. Mechanism and Role of SOX2 Repression in Seminoma: Relevance to Human Germline Specification. Stem Cell Reports. 2016;6:772-783 pubmed publisher |
- chromatin immunoprecipitation; mouse; fig 4b
| Garcia Cuellar M, Büttner C, Bartenhagen C, Dugas M, Slany R. Leukemogenic MLL-ENL Fusions Induce Alternative Chromatin States to Drive a Functionally Dichotomous Group of Target Genes. Cell Rep. 2016;15:310-22 pubmed publisher |
- western blot; human; loading ...; fig s3s
| Taniue K, Kurimoto A, Sugimasa H, Nasu E, Takeda Y, Iwasaki K, et al. Long noncoding RNA UPAT promotes colon tumorigenesis by inhibiting degradation of UHRF1. Proc Natl Acad Sci U S A. 2016;113:1273-8 pubmed publisher |
- western blot; human; 1:1000; fig 5
| Pan H, Guan D, Liu X, Li J, Wang L, Wu J, et al. SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2. Cell Res. 2016;26:190-205 pubmed publisher |
- ChIP-Seq; mouse; fig 2b
- western blot; mouse; fig 1c
| Yang Y, Li W, Hoque M, Hou L, Shen S, Tian B, et al. PAF Complex Plays Novel Subunit-Specific Roles in Alternative Cleavage and Polyadenylation. PLoS Genet. 2016;12:e1005794 pubmed publisher |
- ELISA; Austrofundulus limnaeus; 1:1000; loading ...; fig 5f
| Toni L, Padilla P. Developmentally arrested Austrofundulus limnaeus embryos have changes in post-translational modifications of histone H3. J Exp Biol. 2016;219:544-52 pubmed publisher |
| Schönfeld M, Averilla J, Gunewardena S, Weinman S, Tikhanovich I. Male-Specific Activation of Lysine Demethylases 5B and 5C Mediates Alcohol-Induced Liver Injury and Hepatocyte Dedifferentiation. Hepatol Commun. 2022;6:1373-1391 pubmed publisher |
| Xu S, Wang S, Xing S, Yu D, Rong B, Gao H, et al. KDM5A suppresses PML-RARα target gene expression and APL differentiation through repressing H3K4me2. Blood Adv. 2021;5:3241-3253 pubmed publisher |
| Crispatzu G, Rehimi R, Pachano T, Bleckwehl T, Cruz Molina S, Xiao C, et al. The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo. Nat Commun. 2021;12:4344 pubmed publisher |
| Andrade J, Shi C, Costa A, Choi J, Kim J, Doddaballapur A, et al. Control of endothelial quiescence by FOXO-regulated metabolites. Nat Cell Biol. 2021;23:413-423 pubmed publisher |
| Fitz James M, Tong P, Pidoux A, Özadam H, Yang L, White S, et al. Large domains of heterochromatin direct the formation of short mitotic chromosome loops. elife. 2020;9: pubmed publisher |
| Gao Y, Vasic R, Song Y, Teng R, Liu C, Gbyli R, et al. m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development. Immunity. 2020;52:1007-1021.e8 pubmed publisher |
| Ravasio R, Ceccacci E, Nicosia L, Hosseini A, Rossi P, Barozzi I, et al. Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation. Sci Adv. 2020;6:eaax2746 pubmed publisher |
| Roy A, Ghosh A, Kumar B, Chandran B. IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP. elife. 2019;8: pubmed publisher |
| Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, et al. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing. Nature. 2019;574:553-558 pubmed publisher |
| Kaya Okur H, Wu S, Codomo C, Pledger E, Bryson T, Henikoff J, et al. CUT&Tag for efficient epigenomic profiling of small samples and single cells. Nat Commun. 2019;10:1930 pubmed publisher |
| Kalkan T, Bornelöv S, Mulas C, Diamanti E, Lohoff T, Ralser M, et al. Complementary Activity of ETV5, RBPJ, and TCF3 Drives Formative Transition from Naive Pluripotency. Cell Stem Cell. 2019;24:785-801.e7 pubmed publisher |
| Scelfo A, Fernandez Perez D, Tamburri S, Zanotti M, Lavarone E, Soldi M, et al. Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities. Mol Cell. 2019;74:1037-1052.e7 pubmed publisher |
| Arya R, Gyonjyan S, Harding K, Sarkissian T, Li Y, Zhou L, et al. A Cut/cohesin axis alters the chromatin landscape to facilitate neuroblast death. Development. 2019;146: pubmed publisher |
| Erkek S, Johann P, Finetti M, Drosos Y, Chou H, Zapatka M, et al. Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation. Cancer Cell. 2018;: pubmed publisher |
| Selimoglu Buet D, Rivière J, Ghamlouch H, Bencheikh L, Lacout C, Morabito M, et al. A miR-150/TET3 pathway regulates the generation of mouse and human non-classical monocyte subset. Nat Commun. 2018;9:5455 pubmed publisher |
| Watanabe S, Shimada S, Akiyama Y, Ishikawa Y, Ogura T, Ogawa K, et al. Loss of KDM6A characterizes a poor prognostic subtype of human pancreatic cancer and potentiates HDAC inhibitor lethality. Int J Cancer. 2019;145:192-205 pubmed publisher |
| Koohy H, Bolland D, Matheson L, Schoenfelder S, Stellato C, Dimond A, et al. Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells. Genome Biol. 2018;19:126 pubmed publisher |
| Kong X, Martinez Barricarte R, Kennedy J, Mele F, Lazarov T, Deenick E, et al. Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency. Nat Immunol. 2018;19:973-985 pubmed publisher |
| Fuentes D, Swigut T, Wysocka J. Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation. elife. 2018;7: pubmed publisher |
| Janevska S, Guldener U, Sulyok M, Tudzynski B, Studt L. Set1 and Kdm5 are antagonists for H3K4 methylation and regulators of the major conidiation-specific transcription factor gene ABA1 in Fusarium fujikuroi. Environ Microbiol. 2018;20:3343-3362 pubmed publisher |
| Cho S, Xu J, Sun R, Mumbach M, Carter A, Chen Y, et al. Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element. Cell. 2018;173:1398-1412.e22 pubmed publisher |
| Numata A, Kwok H, Kawasaki A, Li J, Zhou Q, Kerry J, et al. The basic helix-loop-helix transcription factor SHARP1 is an oncogenic driver in MLL-AF6 acute myelogenous leukemia. Nat Commun. 2018;9:1622 pubmed publisher |
| Ran L, Chen Y, Sher J, Wong E, Murphy D, Zhang J, et al. FOXF1 Defines the Core-Regulatory Circuitry in Gastrointestinal Stromal Tumor. Cancer Discov. 2018;8:234-251 pubmed publisher |
| Li P, Wang L, Bennett B, Wang J, Li J, Qin Y, et al. Rif1 promotes a repressive chromatin state to safeguard against endogenous retrovirus activation. Nucleic Acids Res. 2017;45:12723-12738 pubmed publisher |
| Soldi M, Mari T, Nicosia L, Musiani D, Sigismondo G, Cuomo A, et al. Chromatin proteomics reveals novel combinatorial histone modification signatures that mark distinct subpopulations of macrophage enhancers. Nucleic Acids Res. 2017;: pubmed publisher |
| Korb E, Herre M, Zucker Scharff I, Gresack J, Allis C, Darnell R. Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition. Cell. 2017;170:1209-1223.e20 pubmed publisher |
| Dorighi K, Swigut T, Henriques T, Bhanu N, Scruggs B, Nady N, et al. Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation. Mol Cell. 2017;66:568-576.e4 pubmed publisher |
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