Published Application/Species/Sample/Dilution | Reference |
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- ChIP-Seq; mouse; loading ...; fig 1f
| Chandrasekaran S, Espeso Gil S, Loh Y, Javidfar B, Kassim B, Zhu Y, et al. Neuron-specific chromosomal megadomain organization is adaptive to recent retrotransposon expansions. Nat Commun. 2021;12:7243 pubmed publisher
|
- chromatin immunoprecipitation; mouse; 1:1000; fig 1a
| Reddy N, Majidi S, Kong L, Nemera M, Ferguson C, Moore M, et al. CHARGE syndrome protein CHD7 regulates epigenomic activation of enhancers in granule cell precursors and gyrification of the cerebellum. Nat Commun. 2021;12:5702 pubmed publisher
|
- ChIP-Seq; human; loading ...; fig 2b
| Huang C, Lingadahalli S, Morova T, Ozturan D, Hu E, Yu I, et al. Functional mapping of androgen receptor enhancer activity. Genome Biol. 2021;22:149 pubmed publisher
|
- immunocytochemistry; mouse; fig s5d
| Takei Y, Yun J, Zheng S, Ollikainen N, Pierson N, White J, et al. Integrated spatial genomics reveals global architecture of single nuclei. Nature. 2021;590:344-350 pubmed publisher
|
- chromatin immunoprecipitation; human; loading ...; fig 4b
| Zhao Z, Zhang Z, Li J, Dong Q, Xiong J, Li Y, et al. Sustained TNF-α stimulation leads to transcriptional memory that greatly enhances signal sensitivity and robustness. elife. 2020;9: pubmed publisher
|
| Casanova M, Moscatelli M, Chauvière L, Huret C, Samson J, Liyakat Ali T, et al. A primate-specific retroviral enhancer wires the XACT lncRNA into the core pluripotency network in humans. Nat Commun. 2019;10:5652 pubmed publisher
|
- immunocytochemistry; human; 1:500; loading ...; fig 1a
| Farhy C, Hariharan S, Ylanko J, Orozco L, Zeng F, Pass I, et al. Improving drug discovery using image-based multiparametric analysis of the epigenetic landscape. elife. 2019;8: pubmed publisher
|
- ChIP-Seq; Xenopus laevis; loading ...; fig 3e
| Kuznetsov J, Agüero T, Owens D, Kurtenbach S, Field M, Durante M, et al. BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers. Sci Adv. 2019;5:eaax1738 pubmed publisher
|
| Sin Chan P, Mumal I, Suwal T, Ho B, Fan X, Singh I, et al. A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. Cancer Cell. 2019;36:51-67.e7 pubmed publisher
|
- ChIP-Seq; human; loading ...; fig 3a
| O Geen H, Bates S, Carter S, Nisson K, Halmai J, Fink K, et al. Ezh2-dCas9 and KRAB-dCas9 enable engineering of epigenetic memory in a context-dependent manner. Epigenetics Chromatin. 2019;12:26 pubmed publisher
|
- chromatin immunoprecipitation; human; loading ...; fig 3c
| Chowdhry S, Zanca C, Rajkumar U, Koga T, Diao Y, Raviram R, et al. NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling. Nature. 2019;569:570-575 pubmed publisher
|
- ChIP-Seq; mouse; loading ...; fig 6g
| Rajderkar S, Mann J, Panaretos C, Yumoto K, Li H, Mishina Y, et al. Trim33 is required for appropriate development of pre-cardiogenic mesoderm. Dev Biol. 2019;450:101-114 pubmed publisher
|
- ChIP-Seq; human; loading ...; fig 5b
| Stewart E, McEvoy J, Wang H, Chen X, Honnell V, Ocarz M, et al. Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses. Cancer Cell. 2018;34:411-426.e19 pubmed publisher
|
- chromatin immunoprecipitation; mouse; loading ...; fig 8a
| Alabdi L, He M, Yang Q, Norvil A, Gowher H. The transcription factor Vezf1 represses the expression of the antiangiogenic factor Cited2 in endothelial cells. J Biol Chem. 2018;293:11109-11118 pubmed publisher
|
- ChIP-Seq; human; loading ...; fig 3d
| Noutsou M, Li J, Ling J, Jones J, Wang Y, Chen Y, et al. The Cohesin Complex Is Necessary for Epidermal Progenitor Cell Function through Maintenance of Self-Renewal Genes. Cell Rep. 2017;20:3005-3013 pubmed publisher
|
- western blot; human; loading ...; fig 4e
| Yuen K, Slaughter B, Gerton J. Condensin II is anchored by TFIIIC and H3K4me3 in the mammalian genome and supports the expression of active dense gene clusters. Sci Adv. 2017;3:e1700191 pubmed publisher
|
- western blot; human; loading ...; fig 2a
| Zhang X, Li B, Rezaeian A, Xu X, Chou P, Jin G, et al. H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis. Nat Commun. 2017;8:14799 pubmed publisher
|
- ChIP-Seq; mouse; loading ...; fig 1b
| Cruz Molina S, Respuela P, Tebartz C, Kolovos P, Nikolic M, Fueyo R, et al. PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation. Cell Stem Cell. 2017;20:689-705.e9 pubmed publisher
|
- chromatin immunoprecipitation; human; loading ...; fig 3f
- western blot; human; loading ...; fig 3a
| Sherman M, Yu R, Tseng T, Sousa C, Liu S, Truitt M, et al. Stromal cues regulate the pancreatic cancer epigenome and metabolome. Proc Natl Acad Sci U S A. 2017;114:1129-1134 pubmed publisher
|
- immunocytochemistry; human; 1:1000; fig 4
| Singh N, Johnstone D, Martin K, Tempera I, Kaplan M, Denny M. Alterations in nuclear structure promote lupus autoimmunity in a mouse model. Dis Model Mech. 2016;9:885-97 pubmed publisher
|
- chromatin immunoprecipitation; human; 1:100; fig 2
| Weigel C, Veldwijk M, Oakes C, Seibold P, Slynko A, Liesenfeld D, et al. Epigenetic regulation of diacylglycerol kinase alpha promotes radiation-induced fibrosis. Nat Commun. 2016;7:10893 pubmed publisher
|
- ChIP-Seq; zebrafish ; fig 1
| Lin C, Erkek S, Tong Y, Yin L, Federation A, Zapatka M, et al. Active medulloblastoma enhancers reveal subgroup-specific cellular origins. Nature. 2016;530:57-62 pubmed publisher
|
- chromatin immunoprecipitation; human; fig 3
| Flavahan W, Drier Y, Liau B, Gillespie S, Venteicher A, Stemmer Rachamimov A, et al. Insulator dysfunction and oncogene activation in IDH mutant gliomas. Nature. 2016;529:110-4 pubmed publisher
|
| Yuan B, Zhou X, Suzuki K, Ramos Mandujano G, Wang M, Tehseen M, et al. Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing. Nat Commun. 2022;13:3646 pubmed publisher
|
| O Geen H, Tomková M, Combs J, Tilley E, Segal D. Determinants of heritable gene silencing for KRAB-dCas9 + DNMT3 and Ezh2-dCas9 + DNMT3 hit-and-run epigenome editing. Nucleic Acids Res. 2022;50:3239-3253 pubmed publisher
|
| Benbarche S, Lopez C, Salataj E, Aid Z, Thirant C, Laiguillon M, et al. Screening of ETO2-GLIS2-induced Super Enhancers identifies targetable cooperative dependencies in acute megakaryoblastic leukemia. Sci Adv. 2022;8:eabg9455 pubmed publisher
|
| Hota S, Rao K, Blair A, Khalilimeybodi A, Hu K, Thomas R, et al. Brahma safeguards canalization of cardiac mesoderm differentiation. Nature. 2022;602:129-134 pubmed publisher
|
| Liu Y, Wu Z, Zhou J, Ramadurai D, Mortenson K, Aguilera Jimenez E, et al. A predominant enhancer co-amplified with the SOX2 oncogene is necessary and sufficient for its expression in squamous cancer. Nat Commun. 2021;12:7139 pubmed publisher
|
| Geusz R, Wang A, Lam D, Vinckier N, Alysandratos K, Roberts D, et al. Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors. Nat Commun. 2021;12:6636 pubmed publisher
|
| Crispatzu G, Rehimi R, Pachano T, Bleckwehl T, Cruz Molina S, Xiao C, et al. The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo. Nat Commun. 2021;12:4344 pubmed publisher
|
| Liu C, Toth R, Bakr A, Goyal A, Islam M, Breuer K, et al. Epigenetic Modulation of Radiation-Induced Diacylglycerol Kinase Alpha Expression Prevents Pro-Fibrotic Fibroblast Response. Cancers (Basel). 2021;13: pubmed publisher
|
| Setten R, Chomchan P, Epps E, Burnett J, Rossi J. CRED9: A differentially expressed elncRNA regulates expression of transcription factor CEBPA. RNA. 2021;: pubmed publisher
|
| Olsen R, Ireland A, Kastner D, Groves S, Spainhower K, Pozo K, et al. ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer. Genes Dev. 2021;35:847-869 pubmed publisher
|
| Andrade J, Shi C, Costa A, Choi J, Kim J, Doddaballapur A, et al. Control of endothelial quiescence by FOXO-regulated metabolites. Nat Cell Biol. 2021;23:413-423 pubmed publisher
|
| Leistico J, Saini P, Futtner C, Hejna M, Omura Y, Soni P, et al. Epigenomic tensor predicts disease subtypes and reveals constrained tumor evolution. Cell Rep. 2021;34:108927 pubmed publisher
|
| Reizel Y, Morgan A, Gao L, Schug J, Mukherjee S, Garcia M, et al. FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity. Dev Cell. 2021;56:602-612.e4 pubmed publisher
|
| Geusz R, Wang A, Chiou J, Lancman J, Wetton N, Kefalopoulou S, et al. Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development. elife. 2021;10: pubmed publisher
|
| Pomella S, Sreenivas P, Gryder B, Wang L, Milewski D, Cassandri M, et al. Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma. Nat Commun. 2021;12:192 pubmed publisher
|
| Kubo N, Ishii H, Xiong X, Bianco S, Meitinger F, Hu R, et al. Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation. Nat Struct Mol Biol. 2021;28:152-161 pubmed publisher
|
| Wilson M, Reske J, Holladay J, Neupane S, Ngo J, Cuthrell N, et al. ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation. Cell Rep. 2020;33:108366 pubmed publisher
|
| Gomes A, Ilter D, Low V, Endress J, Fernández García J, Rosenzweig A, et al. Age-induced accumulation of methylmalonic acid promotes tumour progression. Nature. 2020;585:283-287 pubmed publisher
|
| Marques J, Gryder B, Pavlovic B, Chung Y, Ngo Q, Frommelt F, et al. NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency. elife. 2020;9: pubmed publisher
|
| Prager B, Vasudevan H, Dixit D, Bernatchez J, Wu Q, Wallace L, et al. The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies. Cancer Discov. 2020;: pubmed publisher
|
| Martire S, Nguyen J, Sundaresan A, Banaszynski L. Differential contribution of p300 and CBP to regulatory element acetylation in mESCs. BMC Mol Cell Biol. 2020;21:55 pubmed publisher
|
| Vander Velde R, Yoon N, Marusyk V, Durmaz A, Dhawan A, Miroshnychenko D, et al. Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures. Nat Commun. 2020;11:2393 pubmed publisher
|
| Levine D, Hong H, Weidemann B, Ramsey K, Affinati A, Schmidt M, et al. NAD+ Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging. Mol Cell. 2020;78:835-849.e7 pubmed publisher
|
| Nanavaty V, Abrash E, Hong C, Park S, Fink E, Li Z, et al. DNA Methylation Regulates Alternative Polyadenylation via CTCF and the Cohesin Complex. Mol Cell. 2020;78:752-764.e6 pubmed publisher
|
| Catizone A, Uzunbas G, Celadova P, Kuang S, Bose D, Sammons M. Locally acting transcription factors regulate p53-dependent cis-regulatory element activity. Nucleic Acids Res. 2020;48:4195-4213 pubmed publisher
|
| Huang Y, Mouttet B, Warnatz H, Risch T, Rietmann F, Frommelt F, et al. The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability. Cancer Cell. 2019;36:630-644.e9 pubmed publisher
|
| Peghaire C, Dufton N, Lang M, Salles Crawley I, Ahnström J, Kalna V, et al. The transcription factor ERG regulates a low shear stress-induced anti-thrombotic pathway in the microvasculature. Nat Commun. 2019;10:5014 pubmed publisher
|
| Mukai J, Cannavó E, Crabtree G, Sun Z, Diamantopoulou A, Thakur P, et al. Recapitulation and Reversal of Schizophrenia-Related Phenotypes in Setd1a-Deficient Mice. Neuron. 2019;104:471-487.e12 pubmed publisher
|
| Nagaraja S, Quezada M, Gillespie S, Arzt M, Lennon J, Woo P, et al. Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State. Mol Cell. 2019;76:965-980.e12 pubmed publisher
|
| Ginley Hidinger M, Carleton J, Rodriguez A, Berrett K, Gertz J. Sufficiency analysis of estrogen responsive enhancers using synthetic activators. Life Sci Alliance. 2019;2: pubmed publisher
|
| Stine R, Sakers A, Teslaa T, Kissig M, Stine Z, Kwon C, et al. PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism. Cell Stem Cell. 2019;25:830-845.e8 pubmed publisher
|
| Jameson N, Ma J, Benitez J, Izurieta A, Han J, Mendez R, et al. Intron 1-Mediated Regulation of EGFR Expression in EGFR-Dependent Malignancies Is Mediated by AP-1 and BET Proteins. Mol Cancer Res. 2019;17:2208-2220 pubmed publisher
|
| Martire S, Gogate A, Whitmill A, Tafessu A, Nguyen J, Teng Y, et al. Phosphorylation of histone H3.3 at serine 31 promotes p300 activity and enhancer acetylation. Nat Genet. 2019;51:941-946 pubmed publisher
|
| Lin Shiao E, Lan Y, Welzenbach J, Alexander K, Zhang Z, Knapp M, et al. p63 establishes epithelial enhancers at critical craniofacial development genes. Sci Adv. 2019;5:eaaw0946 pubmed publisher
|
| Lalioti M, Arbi M, Loukas I, Kaplani K, Kalogeropoulou A, Lokka G, et al. GemC1 governs multiciliogenesis through direct interaction with and transcriptional regulation of p73. J Cell Sci. 2019;132: pubmed publisher
|
| Todd C, Deniz O, Taylor D, Branco M. Functional evaluation of transposable elements as enhancers in mouse embryonic and trophoblast stem cells. elife. 2019;8: pubmed publisher
|
| Sala D, Cunningham T, Stec M, Etxaniz U, Nicoletti C, Dall Agnese A, et al. The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration. Nat Commun. 2019;10:1796 pubmed publisher
|
| Greenberg M, Teissandier A, Walter M, Noordermeer D, Bourc his D. Dynamic enhancer partitioning instructs activation of a growth-related gene during exit from naïve pluripotency. elife. 2019;8: pubmed publisher
|
| Ebrahimi A, Sevinç K, Gürhan Sevinç G, Cribbs A, Philpott M, Uyulur F, et al. Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming. Nat Chem Biol. 2019;15:519-528 pubmed publisher
|
| Augert A, Eastwood E, Ibrahim A, Wu N, Grunblatt E, Basom R, et al. Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition. Sci Signal. 2019;12: pubmed publisher
|
| Xiong L, Wu F, Wu Q, Xu L, Cheung O, Kang W, et al. Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming. Nat Commun. 2019;10:335 pubmed publisher
|
| Garcia Moreno S, Futtner C, Salamone I, Gonen N, Lovell Badge R, Maatouk D. Gonadal supporting cells acquire sex-specific chromatin landscapes during mammalian sex determination. Dev Biol. 2019;446:168-179 pubmed publisher
|
| Watanabe S, Shimada S, Akiyama Y, Ishikawa Y, Ogura T, Ogawa K, et al. Loss of KDM6A characterizes a poor prognostic subtype of human pancreatic cancer and potentiates HDAC inhibitor lethality. Int J Cancer. 2019;145:192-205 pubmed publisher
|
| Hong H, Maury E, Ramsey K, Perelis M, Marcheva B, Omura C, et al. Requirement for NF-κB in maintenance of molecular and behavioral circadian rhythms in mice. Genes Dev. 2018;32:1367-1379 pubmed publisher
|
| Guo Y, Perez A, Hazelett D, Coetzee G, Rhie S, Farnham P. CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops. Genome Biol. 2018;19:160 pubmed publisher
|
| Heinz S, Texari L, Hayes M, Urbanowski M, Chang M, Givarkes N, et al. Transcription Elongation Can Affect Genome 3D Structure. Cell. 2018;174:1522-1536.e22 pubmed publisher
|
| Lopes R, Korkmaz G, Revilla S, van Vliet R, Nagel R, Custers L, et al. CUEDC1 is a primary target of ER? essential for the growth of breast cancer cells. Cancer Lett. 2018;436:87-95 pubmed publisher
|
| Yu Z, Jiang K, Xu Z, Huang H, Qian N, Lu Z, et al. Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration. Cell Stem Cell. 2018;23:487-500.e6 pubmed publisher
|
| Fuentes D, Swigut T, Wysocka J. Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation. elife. 2018;7: pubmed publisher
|
| Nikopoulou C, Panagopoulos G, Sianidis G, Psarra E, Ford E, Thanos D. The Transcription Factor ThPOK Orchestrates Stochastic Interchromosomal Interactions Required for IFNB1 Virus-Inducible Gene Expression. Mol Cell. 2018;71:352-361.e5 pubmed publisher
|
| Liu C, Wang R, He Z, Osteil P, Wilkie E, Yang X, et al. Suppressing Nodal Signaling Activity Predisposes Ectodermal Differentiation of Epiblast Stem Cells. Stem Cell Reports. 2018;11:43-57 pubmed publisher
|
| Hsu E, Pennella M, Zemke N, Eng C, Berk A. Adenovirus E1A Activation Domain Regulates H3 Acetylation Affecting Varied Steps in Transcription at Different Viral Promoters. J Virol. 2018;92: pubmed publisher
|
| Kim H, Tan Y, Ma W, Merkurjev D, Destici E, Ma Q, et al. Pluripotency factors functionally premark cell-type-restricted enhancers in ES cells. Nature. 2018;556:510-514 pubmed publisher
|
| Finley L, Vardhana S, Carey B, Alonso Curbelo D, Koche R, Chen Y, et al. Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity. Nat Cell Biol. 2018;20:565-574 pubmed publisher
|
| Jiang Y, Liu Y, Lu H, Sun S, Jin W, Wang X, et al. Epigenetic activation during T helper 17 cell differentiation is mediated by Tripartite motif containing 28. Nat Commun. 2018;9:1424 pubmed publisher
|
| Feld C, Sahu P, Frech M, Finkernagel F, Nist A, Stiewe T, et al. Combined cistrome and transcriptome analysis of SKI in AML cells identifies SKI as a co-repressor for RUNX1. Nucleic Acids Res. 2018;46:3412-3428 pubmed publisher
|
| Adams S, Maezawa S, Alavattam K, Abe H, Sakashita A, Shroder M, et al. RNF8 and SCML2 cooperate to regulate ubiquitination and H3K27 acetylation for escape gene activation on the sex chromosomes. PLoS Genet. 2018;14:e1007233 pubmed publisher
|
| Li Y, Zheng H, Wang Q, Zhou C, Wei L, Liu X, et al. Genome-wide analyses reveal a role of Polycomb in promoting hypomethylation of DNA methylation valleys. Genome Biol. 2018;19:18 pubmed publisher
|
| Osterwalder M, Barozzi I, Tissières V, Fukuda Yuzawa Y, Mannion B, Afzal S, et al. Enhancer redundancy provides phenotypic robustness in mammalian development. Nature. 2018;554:239-243 pubmed publisher
|
| Xiao X, Fan Y, Li J, Zhang X, Lou X, Dou Y, et al. Guidance of super-enhancers in regulation of IL-9 induction and airway inflammation. J Exp Med. 2018;215:559-574 pubmed publisher
|
| Mack S, Pajtler K, Chavez L, Okonechnikov K, Bertrand K, Wang X, et al. Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling. Nature. 2018;553:101-105 pubmed publisher
|
| Kang H, Jung Y, McElroy K, Zee B, Wallace H, Woolnough J, et al. Bivalent complexes of PRC1 with orthologs of BRD4 and MOZ/MORF target developmental genes in Drosophila. Genes Dev. 2017;31:1988-2002 pubmed publisher
|
| Ryan R, Petrovic J, Rausch D, Zhou Y, Lareau C, Kluk M, et al. A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas. Cell Rep. 2017;21:784-797 pubmed publisher
|
| Zarnegar M, Reinitz F, Newman A, Clarke M. Targeted chromatin ligation, a robust epigenetic profiling technique for small cell numbers. Nucleic Acids Res. 2017;45:e153 pubmed publisher
|
| Carleton J, Berrett K, Gertz J. Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor α-Bound Enhancers. Cell Syst. 2017;5:333-344.e5 pubmed publisher
|
| Mendoza A, Astapova I, Shimizu H, Gallop M, Al Sowaimel L, MacGowan S, et al. NCoR1-independent mechanism plays a role in the action of the unliganded thyroid hormone receptor. Proc Natl Acad Sci U S A. 2017;114:E8458-E8467 pubmed publisher
|
| Korb E, Herre M, Zucker Scharff I, Gresack J, Allis C, Darnell R. Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition. Cell. 2017;170:1209-1223.e20 pubmed publisher
|
| Gupta R, Hadaya J, Trehan A, Zekavat S, Roselli C, Klarin D, et al. A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression. Cell. 2017;170:522-533.e15 pubmed publisher
|
| Miller T, Liau B, Wallace L, Morton A, Xie Q, Dixit D, et al. Transcription elongation factors represent in vivo cancer dependencies in glioblastoma. Nature. 2017;547:355-359 pubmed publisher
|
| Jiang Y, Loh Y, Rajarajan P, Hirayama T, Liao W, Kassim B, et al. The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain. Nat Genet. 2017;49:1239-1250 pubmed publisher
|
| Rusu V, Hoch E, Mercader J, Tenen D, Gymrek M, Hartigan C, et al. Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms. Cell. 2017;170:199-212.e20 pubmed publisher
|
| Dorighi K, Swigut T, Henriques T, Bhanu N, Scruggs B, Nady N, et al. Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation. Mol Cell. 2017;66:568-576.e4 pubmed publisher
|
| Fabbri G, Holmes A, Viganotti M, Scuoppo C, Belver L, Herranz D, et al. Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A. 2017;114:E2911-E2919 pubmed publisher
|
| Liau B, Sievers C, Donohue L, Gillespie S, Flavahan W, Miller T, et al. Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance. Cell Stem Cell. 2017;20:233-246.e7 pubmed publisher
|
| Tak Y, Hung Y, Yao L, Grimmer M, Do A, Bhakta M, et al. Effects on the transcriptome upon deletion of a distal element cannot be predicted by the size of the H3K27Ac peak in human cells. Nucleic Acids Res. 2016;44:4123-33 pubmed publisher
|