Histone H2B antibody (pAb) | Active Motif 39125 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

Histone H2B antibody (pAb)

catalog :

39125

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

citations: 2

Reference
Rico T, Gilles M, Chauderlier A, Comptdaer T, Magnez R, Chwastyniak M, et al. Tau Stabilizes Chromatin Compaction. Front Cell Dev Biol. 2021;9:740550 pubmed publisher
Bao J, Rousseaux S, Shen J, Lin K, Lu Y, Bedford M. The arginine methyltransferase CARM1 represses p300•ACT•CREMτ activity and is required for spermiogenesis. Nucleic Acids Res. 2018;46:4327-4343 pubmed publisher

product information

Catalog Number :

39125

Product Name :

Histone H2B antibody (pAb)

Host Species :

Rabbit

Clonality :

Polyclonal

Size :

200 ul

Isotype :

Serum

CrossReactivity :

Human, Other (Wide Range)

Background :

Histone H2B is one of the core components of the nucleosome. The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points. Histone H1 is responsible for establishing higher-order chromatin structure. Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation; these modifications play a major role in regulating gene expression.

Immunogen :

This Histone H2B antibody was raised against a peptide including the C-terminal region of histone H2B.

Uses :

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.