Histone H2A.Z antibody (pAb) | Active Motif 39113 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

Histone H2A.Z antibody (pAb)

catalog :

39113

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, zebrafish

application :

western blot, immunoprecipitation, chromatin immunoprecipitation, ChIP-Seq

citations: 1

Published Application/Species/Sample/Dilution	Reference
ChIP-Seq; zebrafish ; fig s1a	Murphy P, Wu S, James C, Wike C, Cairns B. Placeholder Nucleosomes Underlie Germline-to-Embryo DNA Methylation Reprogramming. Cell. 2018;172:993-1006.e13 pubmed publisher

product information

Catalog Number :

39113

Product Name :

Histone H2A.Z antibody (pAb)

Host Species :

Rabbit

Clonality :

Polyclonal

Size :

200 ul

Isotype :

Serum

CrossReactivity :

Human, Other (Wide Range)

Background :

The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H2A.Z (H2AZ, H2AFZ) is a histone H2A variant, a protein similar to canonical H2A but with different molecular identity and unique functions. H2A.Z is highly conserved during evolution. It plays an important role in basic cellular mechanisms such as gene activation, chromosome segregation, heterochromatic silencing and progression through the cell cycle. H2A.Z is acetylated at multiple lysine residues in its amino terminus, which may serve to allow H2A.Z to function as an insulator of chromatin domains.

Immunogen :

This Histone H2A.Z antibody was raised against a peptide derived from the C-terminus of human histone H2A.Z.

Uses :

ChIP, ChIP-chip, ChIP-Seq, DB, IP, WB

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.