NF-1B2 antibody (pAb) | Active Motif 39091 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

NF-1B2 antibody (pAb)

catalog :

39091

quantity :

100 ug

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot

product information

Catalog Number :

39091

Product Name :

NF-1B2 antibody (pAb)

Host Species :

Rabbit

Clonality :

Polyclonal

Size :

100 ug

Isotype :

IgG

CrossReactivity :

Human, Rat

Background :

NF-1B2 (NF-1, Nuclear factor-1) is a ubiquitous 47 kDa dimeric DNA-binding protein whose recognition sequence, TGG(C/A)N(5)GCCAA, is found in the genomes of a number of DNA viruses. The same sequence occurs frequently in the human genome. The NF-1 protein stimulates initiation of adenovirus DNA replication in vitro and is capable of stimulating the transcription of genes in cooperation with other factors, such as the estrogen receptor. The Nuclear factor-1 (NF-1) family of transcription factors are encoded by the genes NF-1A, NF-1B2, NF-1C and NF-1X and feature a highly conserved N-terminal DNA binding region and a variable C-terminal transcriptional activation or repression domain. NF-1 binding controls the expression of many target genes, including insulin, TGF-M-NM-2, nucleotide, steroid hormone and vitamin synthetic genes, TNFM-NM-1 and FSH. NF-1 transcripts can be differentially spliced and the resultant protein variants homo- and heterodimerize, allowing for multiple potential transcriptional activation and repression activities.

Immunogen :

This NF-1B2 antibody was raised against a synthetic peptide corresponding to amino acid residues 402-415 of human NF-1B2.

Uses :

Storage :

Antibodies in solution can be stored at -80M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.