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NOTCH3 Knockout Cell Lysate

ABC-KC1307

100 ug

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NOTCH3 Knockout Cell Lysate

Knockout Cell Lysate

100 ug

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NOTCH3

This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008]

Antibody KO Validation; WB

Store KO Cell Lysate at -20℃. Please avoid repeated freeze-thaw cycles.