Anti-C5a [Fab 100] | Absolute Antibody Ab00992-10.6 product information

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product summary

company name :

Absolute Antibody

product type :

antibody

product name :

Anti-C5a [Fab 100]

catalog :

Ab00992-10.6

quantity :

100 μg

clonality :

monoclonal

host :

human

conjugate :

nonconjugated

clone name :

Fab 100

reactivity :

human

product information

Product Name :

Anti-C5a [Fab 100]

Catalog Number :

Ab00992-10.6

Target :

C5a

Antibody Species :

Human

Isotype :

Fab fragment

LCFormat :

kappa

Heavy Chain modification :

His-Tagged

Target Synonyms :

Complement Component 5a; Complement C5; C3 and PZP-Like Alpha-2-Macroglobulin Domain Containing Protein 4; Complement Component 5; C5a Anaphylatoxin; Prepro-C5; CPAMD4; Anaphylatoxin C5a Analog; ECLZB; C5D; C5b

Display Amount :

100 μg

PriceGBP :

385

PriceEUR :

425

Product Type :

Primary Antibody

Clonality :

Monoclonal

ApplicationCodesClone :

ELISA

Immunogen :

A panel of mAbs against the activated complement component C5a was obtained from a filamentous phage M13-Fab display library generated from mice immunized with human rC5a. Fabs isolated from the library after iterative selection against rC5a bound to both rC5a and purified C5. To isolate Fabs specific for neoepitopes expressed on C5a but not on the native complement component C5, the library was rescreened in a competitive manner. The phage Fab library was first incubated with immobilized C5 to deplete C5 reactive Fabs. The C5 nonadherent phage were then incubated with immobilized rC5a in the presence of soluble C5. Bound phage were eluted and subjected to two additional cycles of subtraction with immobilized C5 and selection with immobilized rC5a in the presence of soluble C5. After three cycles of this competitive biopanning, Fabs reactive with rC5a were isolated.

MarketingCategories :

Complement; Immunology

Available Custom Conjugation Options :

AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

UniprotAccessionNo :

P01031

Product Description :

This is a recombinant monoclonal antibody.