Anti-Fas [R-125224] | Absolute Antibody Ab00802-23.0 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Absolute Antibody

product type :

antibody

product name :

Anti-Fas [R-125224]

catalog :

Ab00802-23.0

quantity :

200 μg

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

R-125224

The same clone is also sold as:

Abnova: RAB03437, RAB03438
Invitrogen: MA5-48080, MA5-48079

reactivity :

human

application :

flow cytometry

product information

Product Name :

Anti-Fas [R-125224]

Catalog Number :

Ab00802-23.0

Target :

Fas

Antibody Species :

Rabbit

Isotype :

IgG

LCFormat :

kappa

Target Synonyms :

CD95; h-HFE7A; Tumor necrosis factor receptor superfamily member 6; CD-95; Apo-1; Apo 1; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor

Display Amount :

200 μg

PriceGBP :

285

PriceEUR :

315

Product Type :

Primary Antibody

Clonality :

Monoclonal

ApplicationCodesClone :

Activate; imaging; ELISA; FC

Immunogen :

R-125224 is generated by the humanization of the murine HFE7A anti-Fas antibody by grafting the CDR regions to the framework regions of the human 8E10 antibody and substituting key framework residues from the murine antibody into the 8E10 sequence. The original HFE7A was derived from a hybridoma cell line generated by the fusion of NS1 myeloma cells with splenocytes from Fas-deficient mice which had been immunized with partially purified recombinant human Fas-AIC2A chimera protein consisting of the extracellular region of human Fas antigen (aa -16 to 150) and the extracellular region of the murine IL-3 receptor AIC2 (aa 3-423). The HFE7A hybridoma was selected after screening by flow cytometry for the production of antibodies with the ability to bind to the WR19L12a transformed murine T cell lymphoma cell line expressing human Fas or the L5178YA1 cell line expressing murine Fas, but not to the parental WR19L or L5178Y cells.

MarketingCategories :

RA; oncology; cancer; biosimilar

Available Custom Conjugation Options :

AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

UniprotAccessionNo :

P25445

Product Description :

This is a recombinant monoclonal antibody.