CTLA4 monoclonal antibody, clone ANC152.2/8H5 | Abnova MAB6927 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Abnova

product type :

antibody

product name :

CTLA4 monoclonal antibody, clone ANC152.2/8H5

catalog :

MAB6927

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ANC152.2/8H5

reactivity :

human

application :

flow cytometry, enzyme immunoassay

product information

catalog id :

MAB6927

product name :

CTLA4 monoclonal antibody, clone ANC152.2/8H5

product description :

Mouse monoclonal antibody raised against CTLA4.

clone name :

ANC152.2/8H5

isotype :

IgG1, kappa

gene name :

CTLA4

gene alias :

CD152 CELIAC3 CTLA-4 GSE IDDM12

gene description :

cytotoxic T-lymphocyte-associated protein 4

immunogen :

A mixture of stimulated human PBL's and human CTLA4 Ig fusion protein.

form :

Liquid

recommend dilutions :

The optimal working dilution should be determined by the end user

storage buffer :

In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)

storage instruction :

Store at 4 C.

type clonality :

Antibody

raised in host species :

Mouse

antigen species target species :

Human

specificity :

MAB6927 blocks binding of CD152 (CTLA-4) Ig fusion protein to its CD80/CD86 receptor, and has been reported to modulate suppressive function of human T Regulatory cells in Vitro. It can bind to intracellular CD152 in fixed permeabolized cells. The F(ab')2 form has been used to inhibit proliferation of activated T cells in vitro in a cholera toxin model.

species reactivity cross reactivity :

Human

application key :

Flow Cyt,EIA

size :

100 ug

autodate :

4/1/10

updatetime :

7/20/11 13:33