LBP monoclonal antibody, clone biG 42 | Abnova MAB5661 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Abnova

product type :

antibody

product name :

LBP monoclonal antibody, clone biG 42

catalog :

MAB5661

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

biG 42

reactivity :

human

application :

western blot, ELISA

product information

catalog id :

MAB5661

product name :

LBP monoclonal antibody, clone biG 42

product description :

Mouse monoclonal antibody raised against recombinant LBP.

clone name :

biG 42

isotype :

IgG1

gene name :

LBP

gene alias :

MGC22233

gene description :

lipopolysaccharide binding protein

immunogen :

Recombinant protein corresponding to human LBP.

form :

Lyophilized

recommend dilutions :

ELISA (1:10000). The optimal working dilution should be determined by the end user.

storage buffer :

Lyophilized from PBS

storage instruction :

Store at -20 C on dry atmosphere. After reconstitution with deionized water, store at -20 C or lower. Aliquot to avoid repeated freezing and thawing.

type clonality :

Antibody

raised in host species :

Mouse

antigen species target species :

Human

specificity :

LPS binding protein (LBP) is an approximately 60 KDa acute phase protein that is produced by hepatocytes. This protein strongly binds to LPS and has been shown to play an important role in the handling of LPS by the host. A number of functions of LBP have been reported. First, LBP transfers LPS to the LPS receptor CD14 on mononuclear phagocytes, leading to a 100-1,000-fold increased sensitivity of the cells to LPS. Furthermore, LBP can enhance the response of CD14 negative cells by acceleration of LPS binding to soluble CD14, a complex that stimulates these cells. LBP was demonstrated to protect mice from septic shock caused by LPS or gram negative bacteria.

species reactivity cross reactivity :

Human

application key :

WB,ELISA

size :

100 ug

autodate :

2010-02-01

updatetime :

2011-12-13 15:02:45