CD14 monoclonal antibody, clone biG 4 | Abnova MAB5657 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Abnova

product type :

antibody

product name :

CD14 monoclonal antibody, clone biG 4

catalog :

MAB5657

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

biG 4

reactivity :

human

product information

catalog id :

MAB5657

product name :

CD14 monoclonal antibody, clone biG 4

product description :

Mouse monoclonal antibody raised against CD14.

clone name :

biG 4

isotype :

IgG1

gene name :

CD14

gene alias :

gene description :

CD14 molecule

immunogen :

Monocytes of human and different animals as well as soluble human CD14.

form :

Lyophilized

recommend dilutions :

The optimal working dilution should be determined by the end user

storage buffer :

Lyophilized from PBS

storage instruction :

Store at -20 C on dry atmosphere. After reconstitution with deionized water, store at -20 C or lower. Aliquot to avoid repeated freezing and thawing.

type clonality :

Antibody

raised in host species :

Mouse

antigen species target species :

Human

specificity :

biG 4 represents an excellent marker for CD14. CD14 has been shown to be involved in the LPS-induced cell activation. This antigen is present as a membrane bound form and as soluble antigen, both involved in cell stimulation by LPS. The plasma protein LBP plays an important role in this LPS-CD14 mediated cell activation. Monocytes and PMN are activated by the LBP-LPS complex via membrane CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for Endotoxin.

species reactivity cross reactivity :

Human

application key :

ELISA

size :

100 ug

autodate :

2010-02-01

updatetime :

2011-12-13 15:02:45