Asgr1 monoclonal antibody, clone 8D7 | Abnova MAB5646 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Abnova

product type :

antibody

product name :

Asgr1 monoclonal antibody, clone 8D7

catalog :

MAB5646

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8D7

The same clone is also sold as:

Invitrogen: MA1-40244, MA5-48985
OriGene: AM26170FC-N, AM26170PU-N
BD Biosciences: 563654, 563655
Santa Cruz Biotechnology: sc-52623 AC, sc-52623 HRP, sc-52623

reactivity :

human, rat

application :

western blot, ELISA, flow cytometry, immunohistochemistry - frozen section

product information

catalog id :

MAB5646

product name :

Asgr1 monoclonal antibody, clone 8D7

product description :

Mouse monoclonal antibody raised against native Asgr1.

clone name :

8D7

isotype :

IgG1

gene name :

Asgr1

gene alias :

ASGR MGC108731 RATRHL1 RHL1

gene description :

asialoglycoprotein receptor 1

immunogen :

Native purified rat liver membrane extracts Asgr1.

form :

Liquid

recommend dilutions :

Recommend dilution at 1:10. The optimal working dilution should be determined by the end user.

storage buffer :

In PBS (0.1% BSA, 0.02% sodium azide)

storage instruction :

Store at 4 C.

note :

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

type clonality :

Antibody

raised in host species :

Mouse

antigen species target species :

Rat

specificity :

The asialoglycoprotein receptor (ASGPR) is a transmembrane glycoprotein (42 KDa) which mediates binding, internalisation and degradation of extracellular glycoproteins that have exposed terminal galactose residues. The receptor is expressed on the surface of the hepatocytes in a polar manner, i.e. it is present on the sinusoidal and lateral plasma membranes but not on the bile canalicular membrane. The mammalian hepatic ASGPR mediates the endocytosis and degradation of serum proteins from which terminal sialic residues have been removed. The rat asialoglycoprotein receptor (ASGPR) consists of three polypeptide subunits: rat hepatic lectin (RHL)-1, RHL-2 and RHL-3. The monoclonal antibody 8D7 recognizes a subunit-specific epitope on RHL-1 of rat ASGPR. The monoclonal antibody 8D7 is cross reactive with human ASGPR.

species reactivity cross reactivity :

Human,Rat

application key :

Flow Cyt,WB,ELISA,IHC-Fr

size :

100 ug

autodate :

2/1/10

updatetime :

10/19/11 17:24