ITGA2B monoclonal antibody, clone SZ.22 (FITC) | Abnova MAB5497 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Abnova

product type :

antibody

product name :

ITGA2B monoclonal antibody, clone SZ.22 (FITC)

catalog :

MAB5497

quantity :

100 Reactions

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

SZ.22

reactivity :

human

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

product information

catalog id :

MAB5497

product name :

ITGA2B monoclonal antibody, clone SZ.22 (FITC)

product description :

Mouse monoclonal antibody raised against native ITGA2B.

clone name :

SZ.22

isotype :

IgG1

gene name :

ITGA2B

gene alias :

CD41 CD41B GP2B GPIIb GTA HPA3

gene description :

integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

immunogen :

Native purified ITGA2B from human washed platelets.

form :

Liquid

recommend dilutions :

Immunohistochemistry (Frozen sections) (1:50-1:100). Immunocytochemistry (1:50-1:100). Immunofluorescence (20ul/10 6 platelets/test). Flow Cytometry (20ul/10 6 platelets/test). The optimal working dilution should be determined

storage buffer :

In PBS (2 mg/mL BSA, 0.09% sodium azide)

storage instruction :

Store in the dark at 4 C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing.

note :

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

conjugate tag :

FITC

type clonality :

Antibody

raised in host species :

Mouse

antigen species target species :

Human

specificity :

The CD41 antigen (platelet GPIIb; alpha IIb integrin) is a glycoprotein composed of 2 chains, GPIIb alpha (120 KDa) and GPIIb beta (23KDa), linked by one disulfide bond. CD41 is always non-covalently associated with CD61 (platelet GPIIIa, beta 3 integrin), to form the GPIIb-IIIa (CD41/CD61) complex. CD41 is expressed by platelets, megakaryocytes and by a small subset of CD34+ cells suggesting that CD41/CD61 is the earliest marker of the megakaryocytic lineage. Clone SZ.22 reacts with the alpha chain of CD41. It has been assigned to the CD41 cluster of differentiation at the 5th International Workshop on human Leucocyte Differentiation Antigens in Boston, in 1993.

species reactivity cross reactivity :

Human

application key :

WB,IHC-Fr,ICC,Flow Cyt

size :

100 Reactions

autodate :

2010-01-04

updatetime :

2015-07-29 13:45:26