CD226 monoclonal antibody, clone DX11 | Abnova MAB5270 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Abnova

product type :

antibody

product name :

CD226 monoclonal antibody, clone DX11

catalog :

MAB5270

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DX11

The same clone is also sold as:

Invitrogen: MA5-28150, MA5-28148, MA5-28152, MA5-28149, MA5-28147
OriGene: SM2023F, SM2023LE, SM2023R, SM2023A, SM2023PS, SM2023P, SM2023B
Abcam: ab33397, ab33393
Bio-Rad: MCA2257B, MCA2257SBV515, MCA2257GA, MCA2257SBB700, MCA2257F, MCA2257EL, MCA2257, MCA2257XZ, MCA2257SBV610, MCA2257PE, MCA2257SBV570
BD Biosciences: 559789, 559786, 559788
MyBioSource: MBS211218

reactivity :

human

application :

immunoprecipitation, flow cytometry

product information

catalog id :

MAB5270

product name :

CD226 monoclonal antibody, clone DX11

product description :

Mouse monoclonal antibody raised against native CD226.

clone name :

DX11

isotype :

IgG1

gene name :

CD226

gene alias :

DNAM-1 DNAM1 PTA1 TLiSA1

gene description :

CD226 molecule

immunogen :

Native purified CD226 from human cytotoxic T lymphocyte clone.

form :

Liquid

recommend dilutions :

Flow Cytometry (10ul of the suggested working dilution (1:25-1:100) to label 1x 10 6 cells in 100ul). The optimal working dilution should be determined by the end user.

storage buffer :

In PBS, pH 7.4 (0.09% sodium azide)

storage instruction :

Store at 4 C. For long term storage store at -20 C. Aliquot to avoid repeated freezing and thawing.

note :

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

type clonality :

Antibody

raised in host species :

Mouse

antigen species target species :

Human

specificity :

This antibdoy recognizes human CD226, a 65kD glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes. Clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells (3).

species reactivity cross reactivity :

Human

application key :

IP,Flow Cyt

size :

100 ug

autodate :

1/4/10

updatetime :

10/19/11 17:24