HLA-A25/HLA-Aw32 monoclonal antibody, clone SPM418 | Abnova MAB13069 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Abnova

product type :

antibody

product name :

HLA-A25/HLA-Aw32 monoclonal antibody, clone SPM418

catalog :

MAB13069

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SPM418

reactivity :

human

application :

immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

product information

catalog id :

MAB13069

product name :

HLA-A25/HLA-Aw32 monoclonal antibody, clone SPM418

product description :

Mouse monoclonal antibody raised against native human HLA-A25/HLA-Aw32.

clone name :

SPM418

isotype :

IgG2a, kappa

gene name :

HLA-A

gene alias :

HLAA

gene description :

major histocompatibility complex, class I, A

immunogen :

Normal human peripheral blood lymphocytes of phenotype A1, Aw32, B7, B37, Cw-, Cw-, DR2, DRw10.

protein accession :

P01889;P30443;P30499

form :

Liquid

recommend dilutions :

Flow Cytometry (0.5-1 ug/10 6 cells in 0.1 mL). Immunofluorescence (0.5-1 ug/mL). Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL). The optimal working dilution should be determined by the end user.

storage buffer :

In 10 mM PBS (0.05% BSA, 0.05% sodium azide).

storage instruction :

Store at 4 C.

note :

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

type clonality :

Antibody

raised in host species :

Mouse

antigen species target species :

Human

specificity :

This monoclonal antibody reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition, a reaction was observed with a cell of phenotype A2, Aw31; B17, Bw49. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T cell receptor, inhibition of NK cell cytotoxicity, and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This antibody is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32.

species reactivity cross reactivity :

Human

application key :

IHC-P,IF,Flow Cyt

size :

100 ug

autodate :

2016-02-26

updatetime :

2016-02-26 17:44:06