LASS6 monoclonal antibody (M01), clone 5H7 | Abnova H00253782-M01 product information

product summary

company name :

Abnova

product type :

antibody

product name :

LASS6 monoclonal antibody (M01), clone 5H7

catalog :

H00253782-M01

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5H7

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry - paraffin section

more info or order :

Abnova product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 2a	Hammerschmidt P, Ostkotte D, Nolte H, Gerl M, Jais A, Brunner H, et al. CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity. Cell. 2019;177:1536-1552.e23 pubmed publisher
western blot; human; fig s13	Gerl M, Bittl V, Kirchner S, Sachsenheimer T, Brunner H, Lüchtenborg C, et al. Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions. PLoS ONE. 2016;11:e0153009 pubmed publisher
	Laviad E, Kelly S, Merrill A, Futerman A. Modulation of ceramide synthase activity via dimerization. J Biol Chem. 2012;287:21025-33 pubmed publisher
	Yamane M, Miyazawa K, Moriya S, Abe A, Yamane S. D,L-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (DL-PDMP) increases endoplasmic reticulum stress, autophagy and apoptosis accompanying ceramide accumulation via ceramide synthase 5 protein expression in A549 cells. Biochimie. 2011;93:1446-59 pubmed publisher
	Mesicek J, Lee H, Feldman T, Jiang X, Skobeleva A, Berdyshev E, et al. Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells. Cell Signal. 2010;22:1300-7 pubmed publisher

product information

catalog id :

H00253782-M01

product name :

LASS6 monoclonal antibody (M01), clone 5H7

product description :

Mouse monoclonal antibody raised against a partial recombinant LASS6.

clone name :

5H7

isotype :

IgG2a Kappa

gene name :

LASS6

gene alias :

CerS6 MGC129949 MGC129950

gene description :

LAG1 homolog, ceramide synthase 6

genbank accession :

NM_203463

immunogen :

LASS6 (NP_982288, 62 a.a. ~ 131 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

immunogen sequence protein sequence :

PCAIALNIQANGPQIAPPNAILEKVFTAITKHPDEKRLE
GLSKQLDWDVRSIQRWFRQRRNQEKPSTLTR

protein accession :

NP_982288

storage buffer :

In 1x PBS, pH 7.4

storage instruction :

Store at -20 C or lower. Aliquot to avoid repeated freezing and thawing

quality control testing :

Antibody Reactive Against Recombinant Protein

type clonality :

Antibody

raised in host species :

Mouse

antigen species target species :

Human

species reactivity cross reactivity :

Human

application key :

S-ELISA,ELISA,WB-Re,WB-Ce,IHC-P

size :

100 ug

autodate :

10/10/06

updatetime :

11/15/13 18:29

more info or order :

Abnova product webpage