TMEPAI monoclonal antibody (M01), clone 2A12 | Abnova H00056937-M01 product information

product summary

company name :

Abnova

product type :

antibody

product name :

TMEPAI monoclonal antibody (M01), clone 2A12

catalog :

H00056937-M01

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2A12

reactivity :

human, mouse

application :

western blot, ELISA, flow cytometry

more info or order :

Abnova product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 3b	Kumar P, Sharad S, Petrovics G, Mohamed A, Dobi A, Sreenath T, et al. Loss of miR-449a in ERG-associated prostate cancer promotes the invasive phenotype by inducing SIRT1. Oncotarget. 2016;7:22791-806 pubmed publisher
flow cytometry; mouse; 1:200 western blot; human; fig 4a	Li H, Mohamed A, Sharad S, Umeda E, Song Y, Young D, et al. Silencing of PMEPA1 accelerates the growth of prostate cancer cells through AR, NEDD4 and PTEN. Oncotarget. 2015;6:15137-49 pubmed
	Singha P, Yeh I, Venkatachalam M, Saikumar P. Transforming growth factor-beta (TGF-beta)-inducible gene TMEPAI converts TGF-beta from a tumor suppressor to a tumor promoter in breast cancer. Cancer Res. 2010;70:6377-83 pubmed publisher
	Watanabe Y, Itoh S, Goto T, Ohnishi E, Inamitsu M, Itoh F, et al. TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling. Mol Cell. 2010;37:123-34 pubmed publisher
	Li H, Xu L, Masuda K, Raymundo E, McLeod D, Dobi A, et al. A feedback loop between the androgen receptor and a NEDD4-binding protein, PMEPA1, in prostate cancer cells. J Biol Chem. 2008;283:28988-95 pubmed publisher
	Hirokawa Y, Takagi A, Uchida K, Kozuka Y, Yoneda M, Watanabe M, et al. High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone. Cell Mol Biol Lett. 2007;12:370-7 pubmed publisher

product information

catalog id :

H00056937-M01

product name :

TMEPAI monoclonal antibody (M01), clone 2A12

product description :

Mouse monoclonal antibody raised against a partial recombinant TMEPAI.

clone name :

2A12

isotype :

IgG2a Kappa

gene name :

PMEPA1

gene alias :

STAG1 TMEPAI

gene description :

prostate transmembrane protein, androgen induced 1

genbank accession :

BC015918

immunogen :

TMEPAI (AAH15918, 181 a.a. ~ 280 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

immunogen sequence protein sequence :

NRTIFDSDLMDSARLGGPCPPSSNSGISATCYGSGGRME
GPPPTYSEVIGHYPGSSFQHQQSSGPPSLLEGTRLHHTH
IAPLESAAIWSKEKDKQKGHPL

protein accession :

AAH15918

storage buffer :

In 1x PBS, pH 7.4

storage instruction :

Store at -20 C or lower. Aliquot to avoid repeated freezing and thawing

quality control testing :

Antibody Reactive Against Recombinant Protein

type clonality :

Antibody

raised in host species :

Mouse

antigen species target species :

Human

species reactivity cross reactivity :

Human

application key :

S-ELISA,ELISA,WB-Re

size :

100 ug

autodate :

2006-10-10

updatetime :

2013-11-15 18:29:55

more info or order :

Abnova product webpage