product summary
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company name :
Abnova
product type :
antibody
product name :
BRMS1 monoclonal antibody (M01), clone 2D4-2G11
catalog :
H00025855-M01
quantity :
100 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2D4-2G11
reactivity :
human
application :
western blot, ELISA, immunoprecipitation
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; human
  • western blot; human
Liu Y, Smith P, Jones D. Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis. Mol Cell Biol. 2006;26:8683-96 pubmed
Kramer D, Schön M, Bayerlová M, Bleckmann A, Schön M, Zörnig M, et al. A pro-apoptotic function of iASPP by stabilizing p300 and CBP through inhibition of BRMS1 E3 ubiquitin ligase activity. Cell Death Dis. 2015;6:e1634 pubmed publisher
Cui R, Liu N, He Q, Li W, Huang B, Sun Y, et al. Low BRMS1 expression promotes nasopharyngeal carcinoma metastasis in vitro and in vivo and is associated with poor patient survival. BMC Cancer. 2012;12:376 pubmed publisher
Kim B, Nam H, Pyo K, Jang M, Kim I, Kim D, et al. Breast cancer metastasis suppressor 1 (BRMS1) is destabilized by the Cul3-SPOP E3 ubiquitin ligase complex. Biochem Biophys Res Commun. 2011;415:720-6 pubmed publisher
Smith P, Liu Y, Siefert S, Moskaluk C, Petroni G, Jones D. Breast cancer metastasis suppressor 1 (BRMS1) suppresses metastasis and correlates with improved patient survival in non-small cell lung cancer. Cancer Lett. 2009;276:196-203 pubmed publisher
Rivera J, Megias D, Bravo J. Proteomics-based strategy to delineate the molecular mechanisms of the metastasis suppressor gene BRMS1. J Proteome Res. 2007;6:4006-18 pubmed
product information
catalog id :
H00025855-M01
product name :
BRMS1 monoclonal antibody (M01), clone 2D4-2G11
product description :
Mouse monoclonal antibody raised against a full length recombinant BRMS1.
clone name :
2D4-2G11
isotype :
IgG1 Kappa
gene name :
BRMS1
gene alias :
DKFZp564A063
gene description :
breast cancer metastasis suppressor 1
genbank accession :
BC009834
immunogen :
BRMS1 (AAH09834, 1 a.a. ~ 246 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
immunogen sequence protein sequence :
MPVQPPSKDTEEMEAEGDSAAEMNGEEEESEEERSGSQT
ESEEESSEMDDEDYERRRSECVSEMLDLEKQFSELKEKL
FRERLSQLRLRLEEVGAERAPEYTEPLGGLQRSLKIRIQ
VAGIYKGFCLDVIRNKYECELQGAKQHLESEKLLLYDTL
QGELQERIQRLEEDRQSLDLSSEWWDDKLHARGSSRSWD
SLPPSKRKKAPLVSGPYIVYMLQEIDILEDWTAIKKARA
AVSPQKRKSDGP
protein accession :
AAH09834
storage buffer :
In 1x PBS, pH 7.4
storage instruction :
Store at -20 C or lower. Aliquot to avoid repeated freezing and thawing
quality control testing :
Antibody Reactive Against Recombinant Protein
type clonality :
Antibody
raised in host species :
Mouse
antigen species target species :
Human
species reactivity cross reactivity :
Human
application key :
WB-Ti,S-ELISA,ELISA,WB-Re,WB-Tr,IP
size :
100 ug
autodate :
2008-04-18
updatetime :
2013-11-15 18:40:03
more info or order :
company information
Abnova
9th Fl., No.108, Jhouzih St.
Neihu District. Taipei City
114 Taiwan
sales@abnova.com
https://www.abnova.com
877-853-6098