WWP1 monoclonal antibody (M01), clone 1A7 | Abnova H00011059-M01 product information

product summary

company name :

Abnova

product type :

antibody

product name :

WWP1 monoclonal antibody (M01), clone 1A7

catalog :

H00011059-M01

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1A7

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Abnova product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; fig 2	Qin J, Zhou Z, Chen W, Wang C, Zhang H, Ge G, et al. BAP1 promotes breast cancer cell proliferation and metastasis by deubiquitinating KLF5. Nat Commun. 2015;6:8471 pubmed publisher
immunohistochemistry - paraffin section; human; 1:1000	Basheer W, Harris B, Mentrup H, Abreha M, Thames E, Lea J, et al. Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis. J Mol Cell Cardiol. 2015;88:1-13 pubmed publisher
western blot; human; fig 4	Ge F, Chen W, Qin J, Zhou Z, Liu R, Liu L, et al. Ataxin-3 like (ATXN3L), a member of the Josephin family of deubiquitinating enzymes, promotes breast cancer proliferation by deubiquitinating KrÃ¼ppel-like factor 5 (KLF5). Oncotarget. 2015;6:21369-78 pubmed
	Cao X, Xue L, Han L, Ma L, Chen T, Tong T. WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) delays cellular senescence by promoting p27(Kip1) degradation in human diploid fibroblasts. J Biol Chem. 2011;286:33447-56 pubmed publisher
	Peschiaroli A, Scialpi F, Bernassola F, el Sherbini E, Melino G. The E3 ubiquitin ligase WWP1 regulates ?Np63-dependent transcription through Lys63 linkages. Biochem Biophys Res Commun. 2010;402:425-30 pubmed publisher
	Edwards T, Clowes V, Tsang H, Connell J, Sanderson C, Luzio J, et al. Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5. Biochem J. 2009;423:31-9 pubmed publisher

product information

catalog id :

H00011059-M01

product name :

WWP1 monoclonal antibody (M01), clone 1A7

product description :

Mouse monoclonal antibody raised against a partial recombinant WWP1.

clone name :

1A7

isotype :

IgG2a Kappa

gene name :

WWP1

gene alias :

AIP5 DKFZp434D2111 Tiul1 hSDRP1

gene description :

WW domain containing E3 ubiquitin protein ligase 1

genbank accession :

NM_007013

immunogen :

WWP1 (NP_008944, 152 a.a. ~ 260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

immunogen sequence protein sequence :

CSSSPTIEIQENGDALHENGEPSARTTARLAVEGTNGID
NHVPTSTLVQNSCCSYVVNGDNTPSSPSQVAARPKNTPA
PKPLASEPADDTVNGESSSFAPTDNASVTGT

protein accession :

NP_008944

storage buffer :

In 1x PBS, pH 7.4

storage instruction :

Store at -20 C or lower. Aliquot to avoid repeated freezing and thawing

quality control testing :

Antibody Reactive Against Recombinant Protein

type clonality :

Antibody

raised in host species :

Mouse

antigen species target species :

Human

species reactivity cross reactivity :

Human

application key :

IHC-P,IF,S-ELISA,ELISA,WB-Re,WB-Tr,IP

size :

100 ug

autodate :

2007-09-06

updatetime :

2013-11-15 18:37:01

more info or order :

Abnova product webpage