product summary
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company name :
Abnova
product type :
antibody
product name :
FGL2 monoclonal antibody (M01), clone 6D9
catalog :
H00010875-M01
quantity :
100 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6D9
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, western blot knockout validation
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:1000; loading ...; fig s1c
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig s2b
  • flow cytometry; mouse; loading ...; fig s2e
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig s2a
  • western blot; human; 1:1000; loading ...; fig 8c
Hu J, Wang H, Li X, Liu Y, Mi Y, Kong H, et al. Fibrinogen-like protein 2 aggravates nonalcoholic steatohepatitis via interaction with TLR4, eliciting inflammation in macrophages and inducing hepatic lipid metabolism disorder. Theranostics. 2020;10:9702-9720 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1d
  • western blot; mouse; 1:1000; loading ...; fig 1a
Zhu Y, Zhou J, Feng Y, Chen L, Zhang L, Yang F, et al. Control of Intestinal Inflammation, Colitis-Associated Tumorigenesis, and Macrophage Polarization by Fibrinogen-Like Protein 2. Front Immunol. 2018;9:87 pubmed publisher
Selzner N, Liu H, Boehnert M, Adeyi O, Shalev I, Bartczak A, et al. FGL2/fibroleukin mediates hepatic reperfusion injury by induction of sinusoidal endothelial cell and hepatocyte apoptosis in mice. J Hepatol. 2012;56:153-9 pubmed publisher
Liu Y, Xu S, Xiao F, Xiong Y, Wang X, Gao S, et al. The FGL2/fibroleukin prothrombinase is involved in alveolar macrophage activation in COPD through the MAPK pathway. Biochem Biophys Res Commun. 2010;396:555-61 pubmed publisher
Shalev I, Liu H, Koscik C, Bartczak A, Javadi M, Wong K, et al. Targeted deletion of fgl2 leads to impaired regulatory T cell activity and development of autoimmune glomerulonephritis. J Immunol. 2008;180:249-60 pubmed
O Brien M, Morrison J, Smith T. Expression of prothrombin and protease activated receptors in human myometrium during pregnancy and labor. Biol Reprod. 2008;78:20-6 pubmed
product information
catalog id :
H00010875-M01
product name :
FGL2 monoclonal antibody (M01), clone 6D9
product description :
Mouse monoclonal antibody raised against a partial recombinant FGL2.
clone name :
6D9
isotype :
IgG2a Kappa
gene name :
FGL2
gene alias :
T49 pT49
gene description :
fibrinogen-like 2
genbank accession :
NM_006682
immunogen :
FGL2 (NP_006673, 24 a.a. ~ 123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
immunogen sequence protein sequence :
NNETEEIKDERAKDVCPVRLESRGKCEEAGECPYQVSLP
PLTIQLPKQFSRIEEVFKEVQNLKEIVNSLKKSCQDCKL
QADDNGDPGRNGLLLPSTGAPG
protein accession :
NP_006673
storage buffer :
In 1x PBS, pH 7.4
storage instruction :
Store at -20 C or lower. Aliquot to avoid repeated freezing and thawing
quality control testing :
Antibody Reactive Against Recombinant Protein
type clonality :
Antibody
raised in host species :
Mouse
antigen species target species :
Human
species reactivity cross reactivity :
Human,Mouse,Rat
application key :
IP,S-ELISA,ELISA,WB-Re,WB-Tr,WB-Ce,IHC-P
size :
100 ug
autodate :
10/10/06
updatetime :
11/15/13 18:29
more info or order :
company information
Abnova
9th Fl., No.108, Jhouzih St.
Neihu District. Taipei City
114 Taiwan
sales@abnova.com
https://www.abnova.com
877-853-6098