product summary
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company name :
Abnova
product type :
antibody
product name :
USP15 monoclonal antibody (M01), clone 1C10
catalog :
H00009958-M01
quantity :
100 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1C10
reactivity :
human
application :
western blot, ELISA, immunocytochemistry
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2c
Fielding A, Concannon M, Darling S, Rusilowicz Jones E, Sacco J, Prior I, et al. The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity. Oncogene. 2018;37:2326-2342 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 1b
Chiang C, Pauli E, Biryukov J, Feister K, Meng M, White E, et al. The Human Papillomavirus E6 Oncoprotein Targets USP15 and TRIM25 To Suppress RIG-I-Mediated Innate Immune Signaling. J Virol. 2018;92: pubmed publisher
  • western blot; human
Schweitzer K, Bozko P, Dubiel W, Naumann M. CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha. EMBO J. 2007;26:1532-41 pubmed
Faronato M, Patel V, Darling S, Dearden L, Clague M, Urbé S, et al. The deubiquitylase USP15 stabilizes newly synthesized REST and rescues its expression at mitotic exit. Cell Cycle. 2013;12:1964-77 pubmed publisher
Fernandez Sanchez M, Sechet E, Margottin Goguet F, Rogge L, Bianchi E. The human COP9 signalosome protects ubiquitin-conjugating enzyme 3 (UBC3/Cdc34) from beta-transducin repeat-containing protein (betaTrCP)-mediated degradation. J Biol Chem. 2010;285:17390-7 pubmed publisher
Cayli S, Klug J, Chapiro J, Fröhlich S, Krasteva G, Orel L, et al. COP9 signalosome interacts ATP-dependently with p97/valosin-containing protein (VCP) and controls the ubiquitination status of proteins bound to p97/VCP. J Biol Chem. 2009;284:34944-53 pubmed publisher
Xu M, Takanashi M, Oikawa K, Tanaka M, Nishi H, Isaka K, et al. USP15 plays an essential role for caspase-3 activation during Paclitaxel-induced apoptosis. Biochem Biophys Res Commun. 2009;388:366-71 pubmed publisher
Vos R, Altreuter J, White E, Howley P. The ubiquitin-specific peptidase USP15 regulates human papillomavirus type 16 E6 protein stability. J Virol. 2009;83:8885-92 pubmed publisher
Miyauchi Y, Kato M, Tokunaga F, Iwai K. The COP9/signalosome increases the efficiency of von Hippel-Lindau protein ubiquitin ligase-mediated hypoxia-inducible factor-alpha ubiquitination. J Biol Chem. 2008;283:16622-31 pubmed publisher
product information
catalog id :
H00009958-M01
product name :
USP15 monoclonal antibody (M01), clone 1C10
product description :
Mouse monoclonal antibody raised against a full length recombinant USP15.
clone name :
1C10
isotype :
IgG1 kappa
gene name :
USP15
gene alias :
KIAA0529 MGC131982 MGC149838 MGC74854 UNPH4
gene description :
ubiquitin specific peptidase 15
genbank accession :
BC020688
immunogen :
USP15 (AAH20688, 1 a.a. ~ 235 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
immunogen sequence protein sequence :
MAEGGAADLDTQRSDIATLLKTSLRKGDTWYLVDSRWFK
QWKKYVGFDSWDKYQMGDQNVYPGPIDNSGLLKDGDAQS
LKEHLIDELDYILLPTEGWNKLVSWYTLMEGQEPIARKV
VEQGMFVKHCKVEVYLTELKLCENGNMNNVVTRRFSKAD
TIDTIEKEIRKIFSIPDEKETRLWNKYMSNTFEPLNKPD
STIQDAGLYQGQVLVIEQKNEDGTWPRGPSTPKKPLEQS
C
protein accession :
AAH20688
storage buffer :
In 1x PBS, pH 7.4
storage instruction :
Store at -20 C or lower. Aliquot to avoid repeated freezing and thawing
quality control testing :
Antibody Reactive Against Recombinant Protein
type clonality :
Antibody
raised in host species :
Mouse
antigen species target species :
Human
species reactivity cross reactivity :
Human
application key :
WB-Ce,IF,S-ELISA,ELISA,WB-Re,WB-Tr
size :
100 ug
autodate :
2006-10-10
updatetime :
2013-11-15 18:29:55
more info or order :
company information
Abnova
9th Fl., No.108, Jhouzih St.
Neihu District. Taipei City
114 Taiwan
sales@abnova.com
https://www.abnova.com
877-853-6098