ESPL1 monoclonal antibody (M01), clone 6H6 | Abnova H00009700-M01 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Abnova

product type :

antibody

product name :

ESPL1 monoclonal antibody (M01), clone 6H6

catalog :

H00009700-M01

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6H6

reactivity :

human

application :

western blot, ELISA, immunohistochemistry - paraffin section

citations: 4

Reference
Panigrahi A, Zhang N, Mao Q, Pati D. Calpain-1 cleaves Rad21 to promote sister chromatid separation. Mol Cell Biol. 2011;31:4335-47 pubmed publisher
Mukherjee M, Ge G, Zhang N, Huang E, Nakamura L, Minor M, et al. Separase loss of function cooperates with the loss of p53 in the initiation and progression of T- and B-cell lymphoma, leukemia and aneuploidy in mice. PLoS ONE. 2011;6:e22167 pubmed publisher
Meyer R, Fofanov V, Panigrahi A, Merchant F, Zhang N, Pati D. Overexpression and mislocalization of the chromosomal segregation protein separase in multiple human cancers. Clin Cancer Res. 2009;15:2703-10 pubmed publisher
Zhang N, Ge G, Meyer R, Sethi S, Basu D, Pradhan S, et al. Overexpression of Separase induces aneuploidy and mammary tumorigenesis. Proc Natl Acad Sci U S A. 2008;105:13033-8 pubmed publisher

product information

catalog id :

H00009700-M01

product name :

ESPL1 monoclonal antibody (M01), clone 6H6

product description :

Mouse monoclonal antibody raised against a partial recombinant ESPL1.

clone name :

6H6

isotype :

IgG2a Kappa

gene name :

ESPL1

gene alias :

ESP1 FLJ46492 KIAA0165 SEPARASE SEPARIN

gene description :

extra spindle pole bodies homolog 1 (S. cerevisiae)

genbank accession :

NM_012291

immunogen :

ESPL1 (NP_036423, 586 a.a. ~ 701 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

immunogen sequence protein sequence :

REELQAYKAVRADTGQERFNIICDLLELSPEETPAGAWA
RATHLVELAQVLCYHDFTQQTNCSALDAIREALQLLDSV
RPEAQARDQLLDDKAQALLWLYICTLEAKIQEGIERDR

protein accession :

NP_036423

storage buffer :

In 1x PBS, pH 7.4

storage instruction :

Store at -20 C or lower. Aliquot to avoid repeated freezing and thawing

quality control testing :

Antibody Reactive Against Recombinant Protein

type clonality :

Antibody

raised in host species :

Mouse

antigen species target species :

Human

species reactivity cross reactivity :

Human

application key :

WB-Ce,IHC-P,ELISA,WB-Re

size :

100 ug

autodate :

2008-01-16

updatetime :

2013-11-15 18:37:01