This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abnova
product type :
antibody
product name :
PTN monoclonal antibody (M01), clone 5C3
catalog :
H00005764-M01
quantity :
100 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5C3
reactivity :
human
application :
western blot, ELISA, immunohistochemistry - paraffin section
citations: 4
Reference
Miao J, Ding M, Zhang A, Xiao Z, Qi W, Luo N, et al. Pleiotrophin promotes microglia proliferation and secretion of neurotrophic factors by activating extracellular signal-regulated kinase 1/2 pathway. Neurosci Res. 2012;74:269-76 pubmed publisher
Mikelis C, Lamprou M, Koutsioumpa M, Koutsioubas A, Spyranti Z, Zompra A, et al. A peptide corresponding to the C-terminal region of pleiotrophin inhibits angiogenesis in vivo and in vitro. J Cell Biochem. 2011;112:1532-43 pubmed publisher
Mikelis C, Sfaelou E, Koutsioumpa M, Kieffer N, Papadimitriou E. Integrin alpha(v)beta(3) is a pleiotrophin receptor required for pleiotrophin-induced endothelial cell migration through receptor protein tyrosine phosphatase beta/zeta. FASEB J. 2009;23:1459-69 pubmed publisher
Koutsioumpa M, Hatziapostolou M, Mikelis C, Koolwijk P, Papadimitriou E. Aprotinin stimulates angiogenesis and human endothelial cell migration through the growth factor pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta. Eur J Pharmacol. 2009;602:245-9 pubmed publisher
product information
catalog id :
H00005764-M01
product name :
PTN monoclonal antibody (M01), clone 5C3
product description :
Mouse monoclonal antibody raised against a partial recombinant PTN.
clone name :
5C3
isotype :
IgG1 Kappa
gene name :
PTN
gene alias :
HARP HBGF8 HBNF NEGF1
gene description :
pleiotrophin
genbank accession :
NM_002825
immunogen :
PTN (NP_002816, 45 a.a. ~ 154 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
immunogen sequence protein sequence :
SDCGEWQWSVCVPTSGDCGLGTREGTRTGAECKQTMKTQ
RCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTGSL
KRALHNAECQKTVTISKPCGKLTKPKPQAESK
protein accession :
NP_002816
storage buffer :
In 1x PBS, pH 7.4
storage instruction :
Store at -20 C or lower. Aliquot to avoid repeated freezing and thawing
quality control testing :
Antibody Reactive Against Recombinant Protein
type clonality :
Antibody
raised in host species :
Mouse
antigen species target species :
Human
species reactivity cross reactivity :
Human
application key :
WB-Tr,ELISA,WB-Re,WB-Ce,IHC-P
size :
100 ug
autodate :
4/18/08
updatetime :
11/15/13 18:40
company information
Abnova
9th Fl., No.108, Jhouzih St.
Neihu District. Taipei City
114 Taiwan
sales@abnova.com
https://www.abnova.com
877-853-6098