PCBP2 monoclonal antibody (M07), clone 5F12 | Abnova H00005094-M07 product information

product summary

company name :

Abnova

product type :

antibody

product name :

PCBP2 monoclonal antibody (M07), clone 5F12

catalog :

H00005094-M07

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5F12

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Abnova product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; loading ...; fig 6 western blot; human; loading ...; fig 1a	Yanatori I, Richardson D, Toyokuni S, Kishi F. The iron chaperone poly(rC)-binding protein 2 forms a metabolon with the heme oxygenase 1/cytochrome P450 reductase complex for heme catabolism and iron transfer. J Biol Chem. 2017;292:13205-13229 pubmed publisher
western blot; mouse; 1:500; loading ...; fig 3b	Ryu M, Zhang D, Protchenko O, Shakoury Elizeh M, Philpott C. PCBP1 and NCOA4 regulate erythroid iron storage and heme biosynthesis. J Clin Invest. 2017;127:1786-1797 pubmed publisher
	Fujimura K, Sasaki A, Anderson P. Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules. Nucleic Acids Res. 2012;40:8099-110 pubmed publisher
	Wang L, Jeng K, Lai M. Poly(C)-binding protein 2 interacts with sequences required for viral replication in the hepatitis C virus (HCV) 5' untranslated region and directs HCV RNA replication through circularizing the viral genome. J Virol. 2011;85:7954-64 pubmed publisher
	Lawrence P, Rieder E. Identification of RNA helicase A as a new host factor in the replication cycle of foot-and-mouth disease virus. J Virol. 2009;83:11356-66 pubmed publisher
	Fujimura K, Katahira J, Kano F, Yoneda Y, Murata M. Selective localization of PCBP2 to cytoplasmic processing bodies. Biochim Biophys Acta. 2009;1793:878-87 pubmed publisher
	Süss C, Czupalla C, Winter C, Pursche T, Knoch K, Schroeder M, et al. Rapid changes of mRNA-binding protein levels following glucose and 3-isobutyl-1-methylxanthine stimulation of insulinoma INS-1 cells. Mol Cell Proteomics. 2009;8:393-408 pubmed publisher
	Ghosh D, Srivastava G, Xu D, Schulz L, Roberts R. A link between SIN1 (MAPKAP1) and poly(rC) binding protein 2 (PCBP2) in counteracting environmental stress. Proc Natl Acad Sci U S A. 2008;105:11673-8 pubmed publisher
	Fujimura K, Kano F, Murata M. Identification of PCBP2, a facilitator of IRES-mediated translation, as a novel constituent of stress granules and processing bodies. RNA. 2008;14:425-31 pubmed publisher

product information

catalog id :

H00005094-M07

product name :

PCBP2 monoclonal antibody (M07), clone 5F12

product description :

Mouse monoclonal antibody raised against a full length recombinant PCBP2.

clone name :

5F12

isotype :

IgG2a Kappa

gene name :

PCBP2

gene alias :

HNRPE2 MGC110998 hnRNP-E2

gene description :

poly(rC) binding protein 2

genbank accession :

BC001155

immunogen :

PCBP2 (AAH01155, 1 a.a. ~ 362 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

immunogen sequence protein sequence :

MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKM
REESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDK
LEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGG
CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSII
ECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQDR
YSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAI
PQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKG
YWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQ
MSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVR
LSSETGGMGSS

protein accession :

AAH01155

storage buffer :

In 1x PBS, pH 7.4

storage instruction :

Store at -20 C or lower. Aliquot to avoid repeated freezing and thawing

quality control testing :

Antibody Reactive Against Recombinant Protein

type clonality :

Antibody

raised in host species :

Mouse

antigen species target species :

Human

species reactivity cross reactivity :

Human

application key :

WB-Ce,IHC-P,IF,S-ELISA,ELISA,WB-Re,WB-Tr,RNAi-Ab

size :

100 ug

autodate :

2008-04-18

updatetime :

2013-11-15 18:40:03

more info or order :

Abnova product webpage