NOTCH3 monoclonal antibody (M01), clone 1G5 | Abnova H00004854-M01 product information

product summary

company name :

Abnova

product type :

antibody

product name :

NOTCH3 monoclonal antibody (M01), clone 1G5

catalog :

H00004854-M01

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1G5

reactivity :

human

application :

western blot, ELISA

more info or order :

Abnova product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; human	Park J, Shih I, Wang T. Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer. Cancer Res. 2008;68:8852-60 pubmed publisher
	Dong H, Blaivas M, Wang M. Bidirectional encroachment of collagen into the tunica media in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Brain Res. 2012;1456:64-71 pubmed publisher
	Tada M, Itoh S, Ishii Watabe A, Suzuki T, Kawasaki N. Functional analysis of the Notch ligand Jagged1 missense mutant proteins underlying Alagille syndrome. FEBS J. 2012;279:2096-107 pubmed publisher
	Lee S, Meng H, Elmadhoun O, Blaivas M, Wang M. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy affecting an African American man: identification of a novel 15-base pair NOTCH3 duplication. Arch Neurol. 2011;68:1584-6 pubmed publisher
	Watanabe Hosomi A, Watanabe Y, Tanaka M, Nakagawa M, Mizuno T. Transendocytosis is impaired in CADASIL-mutant NOTCH3. Exp Neurol. 2012;233:303-11 pubmed publisher
	Meng H, Zhang X, Hankenson K, Wang M. Thrombospondin 2 potentiates notch3/jagged1 signaling. J Biol Chem. 2009;284:7866-74 pubmed publisher

product information

catalog id :

H00004854-M01

product name :

NOTCH3 monoclonal antibody (M01), clone 1G5

product description :

Mouse monoclonal antibody raised against a partial recombinant NOTCH3.

clone name :

1G5

isotype :

IgG2a Kappa

gene name :

NOTCH3

gene alias :

CADASIL CASIL

gene description :

Notch homolog 3 (Drosophila)

genbank accession :

NM_000435

immunogen :

NOTCH3 (NP_000426, 47 a.a. ~ 156 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

immunogen sequence protein sequence :

SPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSG
PCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCL
SSPCAHGARCSVGPDGRFLCSCPPGYQGRSCR

protein accession :

NP_000426

storage buffer :

In 1x PBS, pH 7.4

storage instruction :

Store at -20 C or lower. Aliquot to avoid repeated freezing and thawing

quality control testing :

Antibody Reactive Against Recombinant Protein

type clonality :

Antibody

raised in host species :

Mouse

antigen species target species :

Human

species reactivity cross reactivity :

Human

application key :

S-ELISA,ELISA,WB-Re

size :

100 ug

autodate :

10/10/06

updatetime :

11/15/13 18:29

more info or order :

Abnova product webpage