product summary
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company name :
Abnova
product type :
antibody
product name :
LETM1 monoclonal antibody (M03), clone 6F7
catalog :
H00003954-M03
quantity :
100 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6F7
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 5
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; loading ...; fig 1c, 1d, 1f
  • immunocytochemistry; human; loading ...; fig 3b
  • western blot; human; loading ...; fig 4a, s2a
Piao L, Yang Z, Feng Y, Zhang C, Cui C, Xuan Y. LETM1 is a potential biomarker of prognosis in lung non-small cell carcinoma. BMC Cancer. 2019;19:898 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50
Chen L, Yang Y, Liu S, Piao L, Zhang Y, Lin Z, et al. High expression of leucine zipper-EF-hand containing transmembrane protein 1 predicts poor prognosis in head and neck squamous cell carcinoma. Biomed Res Int. 2014;2014:850316 pubmed publisher
Piao L, Li Y, Kim S, Byun H, Huang S, Hwang S, et al. Association of LETM1 and MRPL36 contributes to the regulation of mitochondrial ATP production and necrotic cell death. Cancer Res. 2009;69:3397-404 pubmed publisher
Piao L, Li Y, Kim S, Sohn K, Yang K, Park K, et al. Regulation of OPA1-mediated mitochondrial fusion by leucine zipper/EF-hand-containing transmembrane protein-1 plays a role in apoptosis. Cell Signal. 2009;21:767-77 pubmed publisher
Dimmer K, Navoni F, Casarin A, Trevisson E, Endele S, Winterpacht A, et al. LETM1, deleted in Wolf-Hirschhorn syndrome is required for normal mitochondrial morphology and cellular viability. Hum Mol Genet. 2008;17:201-14 pubmed
product information
catalog id :
H00003954-M03
product name :
LETM1 monoclonal antibody (M03), clone 6F7
product description :
Mouse monoclonal antibody raised against a partial recombinant LETM1.
clone name :
6F7
isotype :
IgG1 Kappa
gene name :
LETM1
gene alias :
-
gene description :
leucine zipper-EF-hand containing transmembrane protein 1
genbank accession :
NM_012318
immunogen :
LETM1 (NP_036450, 601 a.a. ~ 708 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
immunogen sequence protein sequence :
ESKASKRLTKRVQQMIGQIDGLISQLEMDQQAGKLAPAN
GMPTGENVISVAELINAMKQVKHIPESKLTSLAAALDEN
KDGKVNIDDLVKVIELVDKEDVHISTSQVA
protein accession :
NP_036450
storage buffer :
In 1x PBS, pH 7.4
storage instruction :
Store at -20 C or lower. Aliquot to avoid repeated freezing and thawing
quality control testing :
Antibody Reactive Against Recombinant Protein
type clonality :
Antibody
raised in host species :
Mouse
antigen species target species :
Human
species reactivity cross reactivity :
Human
application key :
WB-Tr,IP,S-ELISA,ELISA,WB-Re,WB-Ce,IF,IHC-P
size :
100 ug
autodate :
10/10/06
updatetime :
11/15/13 18:29
more info or order :
company information
Abnova
9th Fl., No.108, Jhouzih St.
Neihu District. Taipei City
114 Taiwan
sales@abnova.com
https://www.abnova.com
877-853-6098