product summary
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company name :
Abnova
product type :
antibody
product name :
ISL1 monoclonal antibody (M05), clone 2E7
catalog :
H00003670-M05
quantity :
100 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2.00E+07
reactivity :
hamsters, human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, ChIP-Seq
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • ChIP-Seq; human; loading ...
Lizio M, Ishizu Y, Itoh M, Lassmann T, Hasegawa A, Kubosaki A, et al. Mapping Mammalian Cell-type-specific Transcriptional Regulatory Networks Using KD-CAGE and ChIP-seq Data in the TC-YIK Cell Line. Front Genet. 2015;6:331 pubmed publisher
  • immunoprecipitation; hamsters; fig 2
  • immunoprecipitation; mouse; fig 6
Yang Z, Zhang Q, Lu Q, Jia Z, Chen P, Ma K, et al. ISL-1 promotes pancreatic islet cell proliferation by forming an ISL-1/Set7/9/PDX-1 complex. Cell Cycle. 2015;14:3820-9 pubmed publisher
  • immunoprecipitation; human
  • western blot; human; fig 2
Zhang Q, Yang Z, Wang W, Guo T, Jia Z, Ma K, et al. A positive feedback regulation of ISL-1 in DLBCL but not in pancreatic ?-cells. Biochem Biophys Res Commun. 2014;449:295-300 pubmed publisher
Shi Q, Ni X, Lei M, Xia Q, Dong Y, Zhang Q, et al. Phosphorylation of islet-1 serine 269 by CDK1 increases its transcriptional activity and promotes cell proliferation in gastric cancer. Mol Med. 2021;27:47 pubmed publisher
Zhang Q, Yang Z, Jia Z, Liu C, Guo C, Lu H, et al. ISL-1 is overexpressed in non-Hodgkin lymphoma and promotes lymphoma cell proliferation by forming a p-STAT3/p-c-Jun/ISL-1 complex. Mol Cancer. 2014;13:181 pubmed publisher
Li B, Jia Z, Wang T, Wang W, Zhang C, Chen P, et al. Interaction of Wnt/?-catenin and notch signaling in the early stage of cardiac differentiation of P19CL6 cells. J Cell Biochem. 2012;113:629-39 pubmed publisher
Guo T, Wang W, Zhang H, Liu Y, Chen P, Ma K, et al. ISL1 promotes pancreatic islet cell proliferation. PLoS ONE. 2011;6:e22387 pubmed publisher
product information
catalog id :
H00003670-M05
product name :
ISL1 monoclonal antibody (M05), clone 2E7
product description :
Mouse monoclonal antibody raised against a partial recombinant ISL1.
clone name :
2.00E+07
isotype :
IgG2a Kappa
gene name :
ISL1
gene alias :
Isl-1
gene description :
ISL LIM homeobox 1
genbank accession :
NM_002202
immunogen :
ISL1 (NP_002193, 63 a.a. ~ 159 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
immunogen sequence protein sequence :
YCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIEC
FRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGA
GDPLSPLHPARPLQMAAEP
protein accession :
NP_002193
storage buffer :
In 1x PBS, pH 7.4
storage instruction :
Store at -20 C or lower. Aliquot to avoid repeated freezing and thawing
quality control testing :
Antibody Reactive Against Recombinant Protein
type clonality :
Antibody
raised in host species :
Mouse
antigen species target species :
Human
species reactivity cross reactivity :
Human,Rat
application key :
ELISA,WB-Re,WB-Ce,IF
size :
100 ug
autodate :
10/10/06
updatetime :
11/15/13 18:29
more info or order :
company information
Abnova
9th Fl., No.108, Jhouzih St.
Neihu District. Taipei City
114 Taiwan
sales@abnova.com
https://www.abnova.com
877-853-6098