DHFR monoclonal antibody (M01), clone 2B10 | Abnova H00001719-M01 product information

product summary

company name :

Abnova

product type :

antibody

product name :

DHFR monoclonal antibody (M01), clone 2B10

catalog :

H00001719-M01

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2B10

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry

more info or order :

Abnova product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:500; loading ...; fig 2a	Li Q, Youn J, Siu K, Murugesan P, Zhang Y, Cai H. Knockout of dihydrofolate reductase in mice induces hypertension and abdominal aortic aneurysm via mitochondrial dysfunction. Redox Biol. 2019;24:101185 pubmed publisher
	Bhabha G, Ekiert D, Jennewein M, Zmasek C, Tuttle L, Kroon G, et al. Divergent evolution of protein conformational dynamics in dihydrofolate reductase. Nat Struct Mol Biol. 2013;20:1243-9 pubmed publisher
	Yoon S, Choi J, Kim J, Shin J, Zhang X, Kang J. Influence of reduced folate carrier and dihydrofolate reductase genes on methotrexate-induced cytotoxicity. Cancer Res Treat. 2010;42:163-71 pubmed publisher
	Vodenicharov M, Laterreur N, Wellinger R. Telomere capping in non-dividing yeast cells requires Yku and Rap1. EMBO J. 2010;29:3007-19 pubmed publisher
	Ionova I, Vasquez Vivar J, Whitsett J, Herrnreiter A, Medhora M, Cooley B, et al. Deficient BH4 production via de novo and salvage pathways regulates NO responses to cytokines in adult cardiac myocytes. Am J Physiol Heart Circ Physiol. 2008;295:H2178-87 pubmed publisher

product information

catalog id :

H00001719-M01

product name :

DHFR monoclonal antibody (M01), clone 2B10

product description :

Mouse monoclonal antibody raised against a partial recombinant DHFR.

clone name :

2B10

isotype :

IgG2a Kappa

gene name :

DHFR

gene alias :

gene description :

dihydrofolate reductase

genbank accession :

BC003584

immunogen :

DHFR (AAH03584, 88 a.a. ~ 187 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

immunogen sequence protein sequence :

HFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAM
NHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPG
VLSDVQEEKGIKYKFEVYEKND

protein accession :

AAH03584

storage buffer :

In 1x PBS, pH 7.4

storage instruction :

Store at -20 C or lower. Aliquot to avoid repeated freezing and thawing

quality control testing :

Antibody Reactive Against Recombinant Protein

type clonality :

Antibody

raised in host species :

Mouse

antigen species target species :

Human

species reactivity cross reactivity :

Human,Rat

application key :

WB-Ce,IF,S-ELISA,ELISA,WB-Re,WB-Tr

size :

100 ug

autodate :

2008-04-24

updatetime :

2013-11-15 18:40:03

more info or order :

Abnova product webpage