CTH monoclonal antibody (M02), clone 2E12-1C10 | Abnova H00001491-M02 product information

product summary

company name :

Abnova

product type :

antibody

product name :

CTH monoclonal antibody (M02), clone 2E12-1C10

catalog :

H00001491-M02

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2E12-1C10

reactivity :

human, mouse

application :

western blot, ELISA, western blot knockout validation

more info or order :

Abnova product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; fig 7	Dickhout J, Carlisle R, Jerome D, Mohammed Ali Z, Jiang H, Yang G, et al. Integrated stress response modulates cellular redox state via induction of cystathionine ?-lyase: cross-talk between integrated stress response and thiol metabolism. J Biol Chem. 2012;287:7603-14 pubmed publisher
western blot; mouse; 1:2000	Jiang H, Hurt K, Breen K, Stabler S, Allen R, Orlicky D, et al. Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap. Biol Open. 2015;4:1154-62 pubmed publisher
	Kar S, Shahshahan H, Hackfort B, Yadav S, Yadav R, Kambis T, et al. Exercise Training Promotes Cardiac Hydrogen Sulfide Biosynthesis and Mitigates Pyroptosis to Prevent High-Fat Diet-Induced Diabetic Cardiomyopathy. Antioxidants (Basel). 2019;8: pubmed publisher
	Qipshidze N, Metreveli N, Mishra P, Lominadze D, Tyagi S. Hydrogen sulfide mitigates cardiac remodeling during myocardial infarction via improvement of angiogenesis. Int J Biol Sci. 2012;8:430-41 pubmed publisher
	Maclean K, Sikora J, Kozich V, Jiang H, Greiner L, Kraus E, et al. A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment. Mol Genet Metab. 2010;101:153-62 pubmed publisher
	d Emmanuele di Villa Bianca R, Sorrentino R, Maffia P, Mirone V, Imbimbo C, Fusco F, et al. Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation. Proc Natl Acad Sci U S A. 2009;106:4513-8 pubmed publisher

product information

catalog id :

H00001491-M02

product name :

CTH monoclonal antibody (M02), clone 2E12-1C10

product description :

Mouse monoclonal antibody raised against a full length recombinant CTH.

clone name :

2E12-1C10

isotype :

IgG1 Kappa

gene name :

CTH

gene alias :

MGC9471

gene description :

cystathionase (cystathionine gamma-lyase)

genbank accession :

BC015807

immunogen :

CTH (AAH15807, 1 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

immunogen sequence protein sequence :

MQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVP
PISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAAL
DGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGT
NRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWI
ETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYF
QRPLALGADISMYSATKYMNGRSDVVMGLVSVNCESLHN
RLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNG
MAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTG
MVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELP
AIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDL
DQALKAAHPPSGSHS

protein accession :

AAH15807

storage buffer :

In 1x PBS, pH 7.4

storage instruction :

Store at -20 C or lower. Aliquot to avoid repeated freezing and thawing

quality control testing :

Antibody Reactive Against Recombinant Protein

type clonality :

Antibody

raised in host species :

Mouse

antigen species target species :

Human

species reactivity cross reactivity :

Human

application key :

WB-Ce,S-ELISA,ELISA,WB-Re

size :

100 ug

autodate :

2008-04-18

updatetime :

2013-11-15 18:40:03

more info or order :

Abnova product webpage