product summary
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company name :
Abnova
product type :
antibody
product name :
CTH monoclonal antibody (M01), clone 4E1-1B7
catalog :
H00001491-M01
quantity :
100 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4E1-1B7
reactivity :
human, mouse
application :
western blot, ELISA
more info or order :
citations: 17
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 5
Li J, Li Q, Du H, Wang Y, You S, Wang F, et al. Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter. Int J Mol Sci. 2015;16:12560-77 pubmed publisher
  • western blot; mouse
Xu Y, Du H, Li J, Xu R, Wang Y, You S, et al. Statins upregulate cystathionine ?-lyase transcription and H2S generation via activating Akt signaling in macrophage. Pharmacol Res. 2014;87:18-25 pubmed publisher
Fu M, Zhang W, Yang G, Wang R. Is cystathionine gamma-lyase protein expressed in the heart?. Biochem Biophys Res Commun. 2012;428:469-74 pubmed publisher
Dufton N, Natividad J, Verdu E, Wallace J. Hydrogen sulfide and resolution of acute inflammation: A comparative study utilizing a novel fluorescent probe. Sci Rep. 2012;2:499 pubmed publisher
Yang G, Li H, Tang G, Wu L, Zhao K, Cao Q, et al. Increased neointimal formation in cystathionine gamma-lyase deficient mice: role of hydrogen sulfide in ?5?1-integrin and matrix metalloproteinase-2 expression in smooth muscle cells. J Mol Cell Cardiol. 2012;52:677-88 pubmed publisher
Li X, Mao X, Hei R, Zhang Z, Wen L, Zhang P, et al. Protective role of hydrogen sulfide against noise-induced cochlear damage: a chronic intracochlear infusion model. PLoS ONE. 2011;6:e26728 pubmed publisher
Yang G, Pei Y, Cao Q, Wang R. MicroRNA-21 represses human cystathionine gamma-lyase expression by targeting at specificity protein-1 in smooth muscle cells. J Cell Physiol. 2012;227:3192-200 pubmed publisher
Yang G, Pei Y, Teng H, Cao Q, Wang R. Specificity protein-1 as a critical regulator of human cystathionine gamma-lyase in smooth muscle cells. J Biol Chem. 2011;286:26450-60 pubmed publisher
Kasparek M, Linden D, Farrugia G, Sarr M. Hydrogen sulfide modulates contractile function in rat jejunum. J Surg Res. 2012;175:234-42 pubmed publisher
Fang L, Zhao J, Chen Y, Ma T, Xu G, Tang C, et al. Hydrogen sulfide derived from periadventitial adipose tissue is a vasodilator. J Hypertens. 2009;27:2174-85 pubmed publisher
Martin G, McKnight G, Dicay M, Coffin C, Ferraz J, Wallace J. Hydrogen sulphide synthesis in the rat and mouse gastrointestinal tract. Dig Liver Dis. 2010;42:103-9 pubmed publisher
Wallace J, Vong L, McKnight W, Dicay M, Martin G. Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats. Gastroenterology. 2009;137:569-78, 578.e1 pubmed publisher
Tripatara P, Patel N, Brancaleone V, Renshaw D, Rocha J, Sepodes B, et al. Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: an in vivo study. Eur J Pharmacol. 2009;606:205-9 pubmed publisher
Feng X, Chen Y, Zhao J, Tang C, Jiang Z, Geng B. Hydrogen sulfide from adipose tissue is a novel insulin resistance regulator. Biochem Biophys Res Commun. 2009;380:153-9 pubmed publisher
Fu Z, Liu X, Geng B, Fang L, Tang C. Hydrogen sulfide protects rat lung from ischemia-reperfusion injury. Life Sci. 2008;82:1196-202 pubmed publisher
Wallace J, Dicay M, McKnight W, Martin G. Hydrogen sulfide enhances ulcer healing in rats. FASEB J. 2007;21:4070-6 pubmed
Schicho R, Krueger D, Zeller F, Von Weyhern C, Frieling T, Kimura H, et al. Hydrogen sulfide is a novel prosecretory neuromodulator in the Guinea-pig and human colon. Gastroenterology. 2006;131:1542-52 pubmed
product information
catalog id :
H00001491-M01
product name :
CTH monoclonal antibody (M01), clone 4E1-1B7
product description :
Mouse monoclonal antibody raised against a full length recombinant CTH.
clone name :
4E1-1B7
isotype :
IgG1 Kappa
gene name :
CTH
gene alias :
MGC9471
gene description :
cystathionase (cystathionine gamma-lyase)
genbank accession :
BC015807
immunogen :
CTH (AAH15807, 1 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
immunogen sequence protein sequence :
MQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVP
PISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAAL
DGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGT
NRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWI
ETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYF
QRPLALGADISMYSATKYMNGRSDVVMGLVSVNCESLHN
RLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNG
MAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTG
MVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELP
AIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDL
DQALKAAHPPSGSHS
protein accession :
AAH15807
storage buffer :
In 1x PBS, pH 7.4
storage instruction :
Store at -20 C or lower. Aliquot to avoid repeated freezing and thawing
quality control testing :
Antibody Reactive Against Recombinant Protein
type clonality :
Antibody
raised in host species :
Mouse
antigen species target species :
Human
species reactivity cross reactivity :
Guinea pig,Human
application key :
WB-Ce,WB-Ti,S-ELISA,ELISA,WB-Re,WB-Tr
size :
100 ug
autodate :
2008-04-30
updatetime :
2013-11-15 18:40:03
more info or order :
company information
Abnova
9th Fl., No.108, Jhouzih St.
Neihu District. Taipei City
114 Taiwan
sales@abnova.com
https://www.abnova.com
877-853-6098